A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report

Dermatomyositis is an inflammatory myopathy presenting with characteristic cutaneous eruption and may be accompanied by proximal muscle weakness. Dermatomyositis may represent a paraneoplastic syndrome in 15%–25% of cases and has rarely been associated with endometrial cancer. Herein, we report a ca...

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Autores principales: Lim, Darosa, Landon-Cardinal, Océane, Belisle, Annie, Davar, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
JCMS Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550948/
https://www.ncbi.nlm.nih.gov/pubmed/33101685
http://dx.doi.org/10.1177/2050313X20961977
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author Lim, Darosa
Landon-Cardinal, Océane
Belisle, Annie
Davar, Sandra
author_facet Lim, Darosa
Landon-Cardinal, Océane
Belisle, Annie
Davar, Sandra
author_sort Lim, Darosa
collection PubMed
description Dermatomyositis is an inflammatory myopathy presenting with characteristic cutaneous eruption and may be accompanied by proximal muscle weakness. Dermatomyositis may represent a paraneoplastic syndrome in 15%–25% of cases and has rarely been associated with endometrial cancer. Herein, we report a case of dermatomyositis with anti-TIF1γ antibodies as the first clinical manifestation revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer after 4 years of remission. Interestingly, dermatomyositis rash completely resolved after lymphadenectomy. This case highlights the importance of early dermatomyositis diagnosis, thorough cancer screening, and that cancer treatment may, in some patients, foster dermatomyositis remission.
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spelling pubmed-75509482020-10-23 A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report Lim, Darosa Landon-Cardinal, Océane Belisle, Annie Davar, Sandra SAGE Open Med Case Rep JCMS Case Report Dermatomyositis is an inflammatory myopathy presenting with characteristic cutaneous eruption and may be accompanied by proximal muscle weakness. Dermatomyositis may represent a paraneoplastic syndrome in 15%–25% of cases and has rarely been associated with endometrial cancer. Herein, we report a case of dermatomyositis with anti-TIF1γ antibodies as the first clinical manifestation revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer after 4 years of remission. Interestingly, dermatomyositis rash completely resolved after lymphadenectomy. This case highlights the importance of early dermatomyositis diagnosis, thorough cancer screening, and that cancer treatment may, in some patients, foster dermatomyositis remission. SAGE Publications 2020-10-10 /pmc/articles/PMC7550948/ /pubmed/33101685 http://dx.doi.org/10.1177/2050313X20961977 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle JCMS Case Report
Lim, Darosa
Landon-Cardinal, Océane
Belisle, Annie
Davar, Sandra
A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report
title A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report
title_full A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report
title_fullStr A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report
title_full_unstemmed A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report
title_short A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report
title_sort case of dermatomyositis with anti-tif1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: a case report
topic JCMS Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550948/
https://www.ncbi.nlm.nih.gov/pubmed/33101685
http://dx.doi.org/10.1177/2050313X20961977
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