Cargando…

Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years

The study aimed to estimate vitamin D intake and plasma/serum 25-hydroxyvitamin D (25(OH)D) concentrations, investigate determinants of 25(OH)D concentrations and compare two 25(OH)D assays. We conducted two nationwide cross-sectional studies in Sweden with 206 school children aged 10–12 years and 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Nälsén, Cecilia, Becker, Wulf, Pearson, Monika, Ridefelt, Peter, Lindroos, Anna Karin, Kotova, Natalia, Mattisson, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550965/
https://www.ncbi.nlm.nih.gov/pubmed/33101664
http://dx.doi.org/10.1017/jns.2020.40
_version_ 1783593078247915520
author Nälsén, Cecilia
Becker, Wulf
Pearson, Monika
Ridefelt, Peter
Lindroos, Anna Karin
Kotova, Natalia
Mattisson, Irene
author_facet Nälsén, Cecilia
Becker, Wulf
Pearson, Monika
Ridefelt, Peter
Lindroos, Anna Karin
Kotova, Natalia
Mattisson, Irene
author_sort Nälsén, Cecilia
collection PubMed
description The study aimed to estimate vitamin D intake and plasma/serum 25-hydroxyvitamin D (25(OH)D) concentrations, investigate determinants of 25(OH)D concentrations and compare two 25(OH)D assays. We conducted two nationwide cross-sectional studies in Sweden with 206 school children aged 10–12 years and 1797 adults aged 18–80 years (n 268 provided blood samples). A web-based dietary record was used to assess dietary intake. Plasma/serum 25(OH)D was analysed by liquid chromatography-mass spectrometry (LC-MS) and immunoassay in adults and LC-MS/MS in children. Most participants reported a vitamin D intake below the average requirement (AR), 16 % of children and 33 % of adults met the AR (7⋅5 μg). In adults, plasma 25(OH)D below 30 and 50 nmol/l were found in 1 and 18 % of participants during the summer period and in 9 and 40 % of participants during the winter period, respectively. In children, serum 25(OH)D below 30 and 50 nmol/l were found in 5 and 42 % of participants (samples collected March–May), respectively. Higher 25(OH)D concentrations were associated with the summer season, vacations in sunny locations (adults), and dietary intake of vitamin D and use of vitamin D supplements, while lower concentrations were associated with a higher BMI and an origin outside of Europe. Concentrations of 25(OH)D were lower using the immunoassay than with the LC-MS assay, but associations with dietary factors and seasonal variability were similar. In conclusion, vitamin D intake was lower than the AR, especially in children. The 25(OH)D concentrations were low in many participants, but few participants had a concentration below 30 nmol/l.
format Online
Article
Text
id pubmed-7550965
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Cambridge University Press
record_format MEDLINE/PubMed
spelling pubmed-75509652020-10-22 Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years Nälsén, Cecilia Becker, Wulf Pearson, Monika Ridefelt, Peter Lindroos, Anna Karin Kotova, Natalia Mattisson, Irene J Nutr Sci Research Article The study aimed to estimate vitamin D intake and plasma/serum 25-hydroxyvitamin D (25(OH)D) concentrations, investigate determinants of 25(OH)D concentrations and compare two 25(OH)D assays. We conducted two nationwide cross-sectional studies in Sweden with 206 school children aged 10–12 years and 1797 adults aged 18–80 years (n 268 provided blood samples). A web-based dietary record was used to assess dietary intake. Plasma/serum 25(OH)D was analysed by liquid chromatography-mass spectrometry (LC-MS) and immunoassay in adults and LC-MS/MS in children. Most participants reported a vitamin D intake below the average requirement (AR), 16 % of children and 33 % of adults met the AR (7⋅5 μg). In adults, plasma 25(OH)D below 30 and 50 nmol/l were found in 1 and 18 % of participants during the summer period and in 9 and 40 % of participants during the winter period, respectively. In children, serum 25(OH)D below 30 and 50 nmol/l were found in 5 and 42 % of participants (samples collected March–May), respectively. Higher 25(OH)D concentrations were associated with the summer season, vacations in sunny locations (adults), and dietary intake of vitamin D and use of vitamin D supplements, while lower concentrations were associated with a higher BMI and an origin outside of Europe. Concentrations of 25(OH)D were lower using the immunoassay than with the LC-MS assay, but associations with dietary factors and seasonal variability were similar. In conclusion, vitamin D intake was lower than the AR, especially in children. The 25(OH)D concentrations were low in many participants, but few participants had a concentration below 30 nmol/l. Cambridge University Press 2020-10-12 /pmc/articles/PMC7550965/ /pubmed/33101664 http://dx.doi.org/10.1017/jns.2020.40 Text en © The Author(s) 2020 http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
spellingShingle Research Article
Nälsén, Cecilia
Becker, Wulf
Pearson, Monika
Ridefelt, Peter
Lindroos, Anna Karin
Kotova, Natalia
Mattisson, Irene
Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years
title Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years
title_full Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years
title_fullStr Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years
title_full_unstemmed Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years
title_short Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10–12 years and adults aged 18–80 years
title_sort vitamin d status in children and adults in sweden: dietary intake and 25-hydroxyvitamin d concentrations in children aged 10–12 years and adults aged 18–80 years
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550965/
https://www.ncbi.nlm.nih.gov/pubmed/33101664
http://dx.doi.org/10.1017/jns.2020.40
work_keys_str_mv AT nalsencecilia vitamindstatusinchildrenandadultsinswedendietaryintakeand25hydroxyvitamindconcentrationsinchildrenaged1012yearsandadultsaged1880years
AT beckerwulf vitamindstatusinchildrenandadultsinswedendietaryintakeand25hydroxyvitamindconcentrationsinchildrenaged1012yearsandadultsaged1880years
AT pearsonmonika vitamindstatusinchildrenandadultsinswedendietaryintakeand25hydroxyvitamindconcentrationsinchildrenaged1012yearsandadultsaged1880years
AT ridefeltpeter vitamindstatusinchildrenandadultsinswedendietaryintakeand25hydroxyvitamindconcentrationsinchildrenaged1012yearsandadultsaged1880years
AT lindroosannakarin vitamindstatusinchildrenandadultsinswedendietaryintakeand25hydroxyvitamindconcentrationsinchildrenaged1012yearsandadultsaged1880years
AT kotovanatalia vitamindstatusinchildrenandadultsinswedendietaryintakeand25hydroxyvitamindconcentrationsinchildrenaged1012yearsandadultsaged1880years
AT mattissonirene vitamindstatusinchildrenandadultsinswedendietaryintakeand25hydroxyvitamindconcentrationsinchildrenaged1012yearsandadultsaged1880years