A defucosylated anti-CD44 monoclonal antibody 5-mG(2a)-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma

CD44 is widely expressed on the surface of most tissues and all hematopoietic cells, and regulates many genes associated with cell adhesion, migration, proliferation, differentiation, and survival. CD44 has also been studied as a therapeutic target in several cancers. Previously, an anti-CD44 monocl...

Descripción completa

Detalles Bibliográficos
Autores principales: Takei, Junko, Kaneko, Mika K., Ohishi, Tomokazu, Hosono, Hideki, Nakamura, Takuro, Yanaka, Miyuki, Sano, Masato, Asano, Teizo, Sayama, Yusuke, Kawada, Manabu, Harada, Hiroyuki, Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550977/
https://www.ncbi.nlm.nih.gov/pubmed/33000243
http://dx.doi.org/10.3892/or.2020.7735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550977/
https://www.ncbi.nlm.nih.gov/pubmed/33000243
http://dx.doi.org/10.3892/or.2020.7735

Ejemplares similares