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A defucosylated anti-CD44 monoclonal antibody 5-mG(2a)-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
CD44 is widely expressed on the surface of most tissues and all hematopoietic cells, and regulates many genes associated with cell adhesion, migration, proliferation, differentiation, and survival. CD44 has also been studied as a therapeutic target in several cancers. Previously, an anti-CD44 monocl...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550977/ https://www.ncbi.nlm.nih.gov/pubmed/33000243 http://dx.doi.org/10.3892/or.2020.7735 |