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Granulomatosis (Wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report

Pulmonary vasculitis can be the manifestation of several systemic illnesses such as primary systemic vasculitis, collagen vascular diseases, and systemic diseases associated with autoantibodies. It may be associated with granulomatous, eosinophilic, lymphoplasmacytic and neutrophilic inflammatory di...

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Autores principales: Lazim, Qusay Jummaa, Atrah, Sinan Shakir Gheni, Mutlag, Khalid Jawad, Alhilfi, Haider Saadoon Qasim, Fahad, Ahmed Muhi, Alshewered, Ahmed Salih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551133/
https://www.ncbi.nlm.nih.gov/pubmed/33082957
http://dx.doi.org/10.1002/rcr2.674
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author Lazim, Qusay Jummaa
Atrah, Sinan Shakir Gheni
Mutlag, Khalid Jawad
Alhilfi, Haider Saadoon Qasim
Fahad, Ahmed Muhi
Alshewered, Ahmed Salih
author_facet Lazim, Qusay Jummaa
Atrah, Sinan Shakir Gheni
Mutlag, Khalid Jawad
Alhilfi, Haider Saadoon Qasim
Fahad, Ahmed Muhi
Alshewered, Ahmed Salih
author_sort Lazim, Qusay Jummaa
collection PubMed
description Pulmonary vasculitis can be the manifestation of several systemic illnesses such as primary systemic vasculitis, collagen vascular diseases, and systemic diseases associated with autoantibodies. It may be associated with granulomatous, eosinophilic, lymphoplasmacytic and neutrophilic inflammatory diseases. In this case report, we describe a 22‐year‐old female presented with intermittent fever, sweating and shivering, haemoptysis, sore throat, shortness of breath, fatigue, loss of appetite, nausea, non‐projectile vomiting, dizziness, and dark coloured urine. The diagnosis of granulomatosis with polyangiitis was made utilizing biochemical and radiological tests. Several pharmacological therapies were tried including rituximab. The patient made a good recovery and was discharged home after 12 days of hospitalization. The knowledge of the main radiographic and computed tomography (CT) scan findings, in association with clinical and laboratory data, often enables non‐invasive diagnosis of pulmonary vasculitis.
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spelling pubmed-75511332020-10-19 Granulomatosis (Wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report Lazim, Qusay Jummaa Atrah, Sinan Shakir Gheni Mutlag, Khalid Jawad Alhilfi, Haider Saadoon Qasim Fahad, Ahmed Muhi Alshewered, Ahmed Salih Respirol Case Rep Case Reports Pulmonary vasculitis can be the manifestation of several systemic illnesses such as primary systemic vasculitis, collagen vascular diseases, and systemic diseases associated with autoantibodies. It may be associated with granulomatous, eosinophilic, lymphoplasmacytic and neutrophilic inflammatory diseases. In this case report, we describe a 22‐year‐old female presented with intermittent fever, sweating and shivering, haemoptysis, sore throat, shortness of breath, fatigue, loss of appetite, nausea, non‐projectile vomiting, dizziness, and dark coloured urine. The diagnosis of granulomatosis with polyangiitis was made utilizing biochemical and radiological tests. Several pharmacological therapies were tried including rituximab. The patient made a good recovery and was discharged home after 12 days of hospitalization. The knowledge of the main radiographic and computed tomography (CT) scan findings, in association with clinical and laboratory data, often enables non‐invasive diagnosis of pulmonary vasculitis. John Wiley & Sons, Ltd 2020-10-13 /pmc/articles/PMC7551133/ /pubmed/33082957 http://dx.doi.org/10.1002/rcr2.674 Text en © 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Lazim, Qusay Jummaa
Atrah, Sinan Shakir Gheni
Mutlag, Khalid Jawad
Alhilfi, Haider Saadoon Qasim
Fahad, Ahmed Muhi
Alshewered, Ahmed Salih
Granulomatosis (Wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report
title Granulomatosis (Wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report
title_full Granulomatosis (Wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report
title_fullStr Granulomatosis (Wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report
title_full_unstemmed Granulomatosis (Wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report
title_short Granulomatosis (Wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report
title_sort granulomatosis (wegener's granulomatosis) with polyangiitis presented as pulmonary manifestation: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551133/
https://www.ncbi.nlm.nih.gov/pubmed/33082957
http://dx.doi.org/10.1002/rcr2.674
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