Binding Sites of Anti-Lcr V Monoclonal Antibodies Are More Critical than the Avidities and Affinities for Passive Protection against Yersinia pestis Infection in a Bubonic Plague Model

Plague is a zoonotic disease that is caused by Yersinia pestis. Monoclonal antibodies (mAbs) that bind to the V-antigen, a virulence factor that is produced by Y. pestis, can passively protect mice from plague. An analysis of protective mAbs that bind to V-antigen was made to assess binding sites, a...

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Detalles Bibliográficos
Autores principales: Amemiya, Kei, Dankmeyer, Jennifer L., Keasey, Sarah L., Trevino, Sylvia R., Wormald, Michael M., Halasohoris, Stephanie A., Ribot, Wilson J., Fetterer, David P., Cote, Christopher K., Worsham, Patricia L., Adamovicz, Jeffrey J., Ulrich, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551159/
https://www.ncbi.nlm.nih.gov/pubmed/32756297
http://dx.doi.org/10.3390/antib9030037

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