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Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents
Background: Oral infectious diseases are typified by dental caries and periodontal diseases and are known to be associated with various systemic diseases. However, clear associations between occlusal disorders and systemic diseases have not yet been established. We investigated the association betwe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551248/ https://www.ncbi.nlm.nih.gov/pubmed/32664631 http://dx.doi.org/10.3390/healthcare8030209 |
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author | Abe, Masanobu Mitani, Akihisa Yao, Atsushi Zong, Liang Hoshi, Kazuto Yanagimoto, Shintaro |
author_facet | Abe, Masanobu Mitani, Akihisa Yao, Atsushi Zong, Liang Hoshi, Kazuto Yanagimoto, Shintaro |
author_sort | Abe, Masanobu |
collection | PubMed |
description | Background: Oral infectious diseases are typified by dental caries and periodontal diseases and are known to be associated with various systemic diseases. However, clear associations between occlusal disorders and systemic diseases have not yet been established. We investigated the association between an awareness of malocclusion and common diseases in late adolescence. Methods: We retrospectively reviewed the data of mandatory medical questionnaires that are a legal requirement of the freshman medical checkup. We collected the data of all the students who completed the questionnaires between April 2017 and 2019. The data were analyzed using the χ(2) test and multivariate analysis was performed with a binomial logistic regression model. Results: The subjects were 9098 students aged 17–19 (mean age 18.3 years). The rate of awareness of malocclusion was 2.14% (195 out of 9098 eligible subjects; 160 males and 35 females). These students had significantly greater rates of allergic rhinitis, asthma, and arrhythmia (p < 0.001). Multivariate analysis revealed significant rates of allergic rhinitis (odds ratio [OR] 2.184, 95% confidence interval [CI]: 1.468–3.250, p < 0.001), asthma (OR 1.843, 95%CI: 1.153–2.945, p = 0.011), and arrhythmia (OR 2.809, 95%CI: 1.083–7.288, p = 0.034) among students with an awareness of malocclusion. Conclusion: We identified close associations between an awareness of malocclusion and systemic diseases including allergic rhinitis, asthma, and arrhythmia in the late adolescent population. These results reinforce the associations between malocclusion and allergic rhinitis and asthma, as well as providing novel insight into the association of malocclusion and arrhythmia. However, further research is necessary to confirm the associations and explore the mechanisms underlying these associations. |
format | Online Article Text |
id | pubmed-7551248 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75512482020-10-16 Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents Abe, Masanobu Mitani, Akihisa Yao, Atsushi Zong, Liang Hoshi, Kazuto Yanagimoto, Shintaro Healthcare (Basel) Article Background: Oral infectious diseases are typified by dental caries and periodontal diseases and are known to be associated with various systemic diseases. However, clear associations between occlusal disorders and systemic diseases have not yet been established. We investigated the association between an awareness of malocclusion and common diseases in late adolescence. Methods: We retrospectively reviewed the data of mandatory medical questionnaires that are a legal requirement of the freshman medical checkup. We collected the data of all the students who completed the questionnaires between April 2017 and 2019. The data were analyzed using the χ(2) test and multivariate analysis was performed with a binomial logistic regression model. Results: The subjects were 9098 students aged 17–19 (mean age 18.3 years). The rate of awareness of malocclusion was 2.14% (195 out of 9098 eligible subjects; 160 males and 35 females). These students had significantly greater rates of allergic rhinitis, asthma, and arrhythmia (p < 0.001). Multivariate analysis revealed significant rates of allergic rhinitis (odds ratio [OR] 2.184, 95% confidence interval [CI]: 1.468–3.250, p < 0.001), asthma (OR 1.843, 95%CI: 1.153–2.945, p = 0.011), and arrhythmia (OR 2.809, 95%CI: 1.083–7.288, p = 0.034) among students with an awareness of malocclusion. Conclusion: We identified close associations between an awareness of malocclusion and systemic diseases including allergic rhinitis, asthma, and arrhythmia in the late adolescent population. These results reinforce the associations between malocclusion and allergic rhinitis and asthma, as well as providing novel insight into the association of malocclusion and arrhythmia. However, further research is necessary to confirm the associations and explore the mechanisms underlying these associations. MDPI 2020-07-12 /pmc/articles/PMC7551248/ /pubmed/32664631 http://dx.doi.org/10.3390/healthcare8030209 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Abe, Masanobu Mitani, Akihisa Yao, Atsushi Zong, Liang Hoshi, Kazuto Yanagimoto, Shintaro Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents |
title | Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents |
title_full | Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents |
title_fullStr | Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents |
title_full_unstemmed | Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents |
title_short | Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents |
title_sort | awareness of malocclusion is closely associated with allergic rhinitis, asthma, and arrhythmia in late adolescents |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551248/ https://www.ncbi.nlm.nih.gov/pubmed/32664631 http://dx.doi.org/10.3390/healthcare8030209 |
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