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Long-term supplementation of dehydroepiandrosterone improved depressive-like behaviors by increasing BDNF expression in the hippocampus in ovariectomized rats

OBJECTIVE: Dehydroepiandrosterone (DHEA), a precursor of estrogen, partially exhibits its biological effect after conversion to estrogen. Its biological significance in perimenopausal depressive disorder or postpartum depression remains unknown. Here, we observed the effects of long-term supplementa...

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Detalles Bibliográficos
Autores principales:	Wu, Siyang, Ye, Mei, Li, Zhulin, Bu, Shizhong, Zhang, Yisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551328/ https://www.ncbi.nlm.nih.gov/pubmed/33083624 http://dx.doi.org/10.1016/j.heliyon.2020.e05180

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