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ECM deposition is driven by caveolin-1–dependent regulation of exosomal biogenesis and cargo sorting
The composition and physical properties of the extracellular matrix (ECM) critically influence tumor progression, but the molecular mechanisms underlying ECM layering are poorly understood. Tumor–stroma interaction critically depends on cell communication mediated by exosomes, small vesicles generat...
Autores principales: | Albacete-Albacete, Lucas, Navarro-Lérida, Inmaculada, López, Juan Antonio, Martín-Padura, Inés, Astudillo, Alma M., Ferrarini, Alessia, Van-Der-Heyden, Michael, Balsinde, Jesús, Orend, Gertraud, Vázquez, Jesús, del Pozo, Miguel Ángel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551399/ https://www.ncbi.nlm.nih.gov/pubmed/33053168 http://dx.doi.org/10.1083/jcb.202006178 |
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