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Production of Highly Active Recombinant Dermonecrotic Toxin of Bordetella Pertussis

Pathogenic Bordetella bacteria release a neurotropic dermonecrotic toxin (DNT) that is endocytosed into animal cells and permanently activates the Rho family GTPases by polyamination or deamidation of the glutamine residues in their switch II regions (e.g., Gln63 of RhoA). DNT was found to enable hi...

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Detalles Bibliográficos
Autores principales:	Stanek, Ondrej, Linhartova, Irena, Holubova, Jana, Bumba, Ladislav, Gardian, Zdenko, Malandra, Anna, Bockova, Barbora, Teruya, Shihono, Horiguchi, Yasuhiko, Osicka, Radim, Sebo, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551409/ https://www.ncbi.nlm.nih.gov/pubmed/32942577 http://dx.doi.org/10.3390/toxins12090596

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