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Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review
Ocoxin Oral Solution (OOS) is a nutritional supplement whose formulation includes several plant extracts and natural products with demonstrated antitumoral properties. This review summarizes the antitumoral action of the different constituents of OOS. The action of this formulation on different prec...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551453/ https://www.ncbi.nlm.nih.gov/pubmed/32878230 http://dx.doi.org/10.3390/nu12092661 |
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author | Pandiella-Alonso, Atanasio Díaz-Rodríguez, Elena Sanz, Eduardo |
author_facet | Pandiella-Alonso, Atanasio Díaz-Rodríguez, Elena Sanz, Eduardo |
author_sort | Pandiella-Alonso, Atanasio |
collection | PubMed |
description | Ocoxin Oral Solution (OOS) is a nutritional supplement whose formulation includes several plant extracts and natural products with demonstrated antitumoral properties. This review summarizes the antitumoral action of the different constituents of OOS. The action of this formulation on different preclinical models as well as clinical trials is reviewed, paying special attention to the mechanism of action and quality of life improvement properties of this nutritional supplement. Molecularly, its mode of action includes a double edge role on tumor biology, that involves a slowdown in cell proliferation accompanied by cell death induction. Given the safety and good tolerability of OOS, and its potentiation of the antitumoral effect of other standard of care drugs, OOS may be used in the oncology clinic in combination with conventional therapies. |
format | Online Article Text |
id | pubmed-7551453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75514532020-10-14 Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review Pandiella-Alonso, Atanasio Díaz-Rodríguez, Elena Sanz, Eduardo Nutrients Review Ocoxin Oral Solution (OOS) is a nutritional supplement whose formulation includes several plant extracts and natural products with demonstrated antitumoral properties. This review summarizes the antitumoral action of the different constituents of OOS. The action of this formulation on different preclinical models as well as clinical trials is reviewed, paying special attention to the mechanism of action and quality of life improvement properties of this nutritional supplement. Molecularly, its mode of action includes a double edge role on tumor biology, that involves a slowdown in cell proliferation accompanied by cell death induction. Given the safety and good tolerability of OOS, and its potentiation of the antitumoral effect of other standard of care drugs, OOS may be used in the oncology clinic in combination with conventional therapies. MDPI 2020-08-31 /pmc/articles/PMC7551453/ /pubmed/32878230 http://dx.doi.org/10.3390/nu12092661 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pandiella-Alonso, Atanasio Díaz-Rodríguez, Elena Sanz, Eduardo Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review |
title | Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review |
title_full | Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review |
title_fullStr | Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review |
title_full_unstemmed | Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review |
title_short | Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review |
title_sort | antitumoral properties of the nutritional supplement ocoxin oral solution: a comprehensive review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551453/ https://www.ncbi.nlm.nih.gov/pubmed/32878230 http://dx.doi.org/10.3390/nu12092661 |
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