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The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding
Although dietary fiber treatment alters the gut microbiota and its metabolite production, it is unclear whether or not exercise habits can have a supplemental effect on changes in gut microbiota in dietary fiber-treated mice. To clarify the supplemental effect of voluntary exercise on gut microbiota...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551544/ https://www.ncbi.nlm.nih.gov/pubmed/32825157 http://dx.doi.org/10.3390/nu12092508 |
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author | Aoki, Takafumi Oyanagi, Eri Watanabe, Chihiro Kobiki, Nanako Miura, Suzuka Yokogawa, Yuka Kitamura, Hiromi Teramoto, Fusako Kremenik, Michael J. Yano, Hiromi |
author_facet | Aoki, Takafumi Oyanagi, Eri Watanabe, Chihiro Kobiki, Nanako Miura, Suzuka Yokogawa, Yuka Kitamura, Hiromi Teramoto, Fusako Kremenik, Michael J. Yano, Hiromi |
author_sort | Aoki, Takafumi |
collection | PubMed |
description | Although dietary fiber treatment alters the gut microbiota and its metabolite production, it is unclear whether or not exercise habits can have a supplemental effect on changes in gut microbiota in dietary fiber-treated mice. To clarify the supplemental effect of voluntary exercise on gut microbiota in partially hydrolyzed guar gum (PHGG), which is a soluble dietary fiber, treated mice under high-fat diet (HFD) feeding, 4-week-old male C57BL/6J mice (n = 80) were randomly divided into two dietary groups: the control-diet (CD) and HFD. Then, each dietary group was treated with or without PHGG, and with or without wheel running. After the experimental period, measurement of maximal oxygen consumption, a glucose tolerance test and fecal materials collection for analysis of gut microbiota were carried out. Voluntary exercise load in PHGG treatment under HFD feeding showed the supplemental effect of exercise on obesity (p < 0.01) and glucose tolerance (p < 0.01). Additionally, in both CD and HFD groups, voluntary exercise accelerated the decrease in the Firmicutes/Bacteroidetes ratio in mice fed with PHGG (p < 0.01). These findings suggest that voluntary exercise might activate the prevention of obesity and insulin resistance more via change in gut microbiota in mice administrated with PHGG. |
format | Online Article Text |
id | pubmed-7551544 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75515442020-10-14 The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding Aoki, Takafumi Oyanagi, Eri Watanabe, Chihiro Kobiki, Nanako Miura, Suzuka Yokogawa, Yuka Kitamura, Hiromi Teramoto, Fusako Kremenik, Michael J. Yano, Hiromi Nutrients Article Although dietary fiber treatment alters the gut microbiota and its metabolite production, it is unclear whether or not exercise habits can have a supplemental effect on changes in gut microbiota in dietary fiber-treated mice. To clarify the supplemental effect of voluntary exercise on gut microbiota in partially hydrolyzed guar gum (PHGG), which is a soluble dietary fiber, treated mice under high-fat diet (HFD) feeding, 4-week-old male C57BL/6J mice (n = 80) were randomly divided into two dietary groups: the control-diet (CD) and HFD. Then, each dietary group was treated with or without PHGG, and with or without wheel running. After the experimental period, measurement of maximal oxygen consumption, a glucose tolerance test and fecal materials collection for analysis of gut microbiota were carried out. Voluntary exercise load in PHGG treatment under HFD feeding showed the supplemental effect of exercise on obesity (p < 0.01) and glucose tolerance (p < 0.01). Additionally, in both CD and HFD groups, voluntary exercise accelerated the decrease in the Firmicutes/Bacteroidetes ratio in mice fed with PHGG (p < 0.01). These findings suggest that voluntary exercise might activate the prevention of obesity and insulin resistance more via change in gut microbiota in mice administrated with PHGG. MDPI 2020-08-19 /pmc/articles/PMC7551544/ /pubmed/32825157 http://dx.doi.org/10.3390/nu12092508 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Aoki, Takafumi Oyanagi, Eri Watanabe, Chihiro Kobiki, Nanako Miura, Suzuka Yokogawa, Yuka Kitamura, Hiromi Teramoto, Fusako Kremenik, Michael J. Yano, Hiromi The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding |
title | The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding |
title_full | The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding |
title_fullStr | The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding |
title_full_unstemmed | The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding |
title_short | The Effect of Voluntary Exercise on Gut Microbiota in Partially Hydrolyzed Guar Gum Intake Mice under High-Fat Diet Feeding |
title_sort | effect of voluntary exercise on gut microbiota in partially hydrolyzed guar gum intake mice under high-fat diet feeding |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551544/ https://www.ncbi.nlm.nih.gov/pubmed/32825157 http://dx.doi.org/10.3390/nu12092508 |
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