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Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats

In recent years, dietary products with quinoa and buckwheat have attracted attention mostly due to the high nutritive value of their protein fraction. However, their dietary effect on intestinal microbiota activity and related systemic responses are still poorly understood. Therefore, a 2 week study...

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Autores principales: Fotschki, Bartosz, Juśkiewicz, Jerzy, Jurgoński, Adam, Amarowicz, Ryszard, Opyd, Paulina, Bez, Jürgen, Muranyi, Isabel, Lykke Petersen, Iben, Laparra Llopis, Moisés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551680/
https://www.ncbi.nlm.nih.gov/pubmed/32932953
http://dx.doi.org/10.3390/nu12092781
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author Fotschki, Bartosz
Juśkiewicz, Jerzy
Jurgoński, Adam
Amarowicz, Ryszard
Opyd, Paulina
Bez, Jürgen
Muranyi, Isabel
Lykke Petersen, Iben
Laparra Llopis, Moisés
author_facet Fotschki, Bartosz
Juśkiewicz, Jerzy
Jurgoński, Adam
Amarowicz, Ryszard
Opyd, Paulina
Bez, Jürgen
Muranyi, Isabel
Lykke Petersen, Iben
Laparra Llopis, Moisés
author_sort Fotschki, Bartosz
collection PubMed
description In recent years, dietary products with quinoa and buckwheat have attracted attention mostly due to the high nutritive value of their protein fraction. However, their dietary effect on intestinal microbiota activity and related systemic responses are still poorly understood. Therefore, a 2 week study of twenty-eight growing male Wistar rats was conducted to investigate the effects of quinoa (QU) and buckwheat (BK) protein-rich flours on the growth parameters, intestinal microbial activity, plasma lipid profile, and inflammatory markers. The biological value of protein and body weight gain were considerably increased in the QU and BK groups compared with those in the soy protein isolate group. Moreover, both flours increased the microbial activity of α-glucosidase, β-glucosidase, and α-galactosidase and the concentration of short-chain fatty acids in the caecum. The studied flours favourably reduced the plasma total cholesterol and LDL cholesterol. In rats fed a diet with QU, elevated levels of plasma interleukin 6 and alanine transaminase were observed. The effect of QU on inflammatory markers may be related to the increased expression of aryl hydrocarbon receptor in the liver and to the decreased level of plasma albumin. In conclusion, quinoa and buckwheat protein-rich flours are valuable sources of proteins that favourably affect growth parameters, gut metabolism, and blood lipid profile in rats; however, only the buckwheat flour has no effect on inflammatory processes.
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spelling pubmed-75516802020-10-14 Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats Fotschki, Bartosz Juśkiewicz, Jerzy Jurgoński, Adam Amarowicz, Ryszard Opyd, Paulina Bez, Jürgen Muranyi, Isabel Lykke Petersen, Iben Laparra Llopis, Moisés Nutrients Article In recent years, dietary products with quinoa and buckwheat have attracted attention mostly due to the high nutritive value of their protein fraction. However, their dietary effect on intestinal microbiota activity and related systemic responses are still poorly understood. Therefore, a 2 week study of twenty-eight growing male Wistar rats was conducted to investigate the effects of quinoa (QU) and buckwheat (BK) protein-rich flours on the growth parameters, intestinal microbial activity, plasma lipid profile, and inflammatory markers. The biological value of protein and body weight gain were considerably increased in the QU and BK groups compared with those in the soy protein isolate group. Moreover, both flours increased the microbial activity of α-glucosidase, β-glucosidase, and α-galactosidase and the concentration of short-chain fatty acids in the caecum. The studied flours favourably reduced the plasma total cholesterol and LDL cholesterol. In rats fed a diet with QU, elevated levels of plasma interleukin 6 and alanine transaminase were observed. The effect of QU on inflammatory markers may be related to the increased expression of aryl hydrocarbon receptor in the liver and to the decreased level of plasma albumin. In conclusion, quinoa and buckwheat protein-rich flours are valuable sources of proteins that favourably affect growth parameters, gut metabolism, and blood lipid profile in rats; however, only the buckwheat flour has no effect on inflammatory processes. MDPI 2020-09-11 /pmc/articles/PMC7551680/ /pubmed/32932953 http://dx.doi.org/10.3390/nu12092781 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fotschki, Bartosz
Juśkiewicz, Jerzy
Jurgoński, Adam
Amarowicz, Ryszard
Opyd, Paulina
Bez, Jürgen
Muranyi, Isabel
Lykke Petersen, Iben
Laparra Llopis, Moisés
Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats
title Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats
title_full Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats
title_fullStr Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats
title_full_unstemmed Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats
title_short Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats
title_sort protein-rich flours from quinoa and buckwheat favourably affect the growth parameters, intestinal microbial activity and plasma lipid profile of rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551680/
https://www.ncbi.nlm.nih.gov/pubmed/32932953
http://dx.doi.org/10.3390/nu12092781
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