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Obese Adipose Tissue Secretion Induces Inflammation in Preadipocytes: Role of Toll-Like Receptor-4

In obesity, the dysfunctional adipose tissue (AT) releases increased levels of proinflammatory adipokines such as TNFα, IL-6, and IL-1β and free fatty acids (FFAs), characterizing a chronic, low-grade inflammation. Whilst FFAs and proinflammatory adipokines are known to elicit an inflammatory respon...

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Detalles Bibliográficos
Autores principales: Renovato-Martins, Mariana, Moreira-Nunes, Catharina, Atella, Georgia C., Barja-Fidalgo, Christina, de Moraes, João Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551792/
https://www.ncbi.nlm.nih.gov/pubmed/32947825
http://dx.doi.org/10.3390/nu12092828