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Germ-Free Conditions Modulate Host Purine Metabolism, Exacerbating Adenine-Induced Kidney Damage
Alterations in microbiota are known to affect kidney disease conditions. We have previously shown that germ-free conditions exacerbated adenine-induced kidney damage in mice; however, the mechanism by which this occurs has not been elucidated. To explore this mechanism, we examined the influence of...
Autores principales: | Mishima, Eikan, Ichijo, Mariko, Kawabe, Takeshi, Kikuchi, Koichi, Akiyama, Yukako, Toyohara, Takafumi, Suzuki, Takehiro, Suzuki, Chitose, Asao, Atsuko, Ishii, Naoto, Fukuda, Shinji, Abe, Takaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551802/ https://www.ncbi.nlm.nih.gov/pubmed/32859011 http://dx.doi.org/10.3390/toxins12090547 |
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