Generation of Combinatorial Lentiviral Vectors Expressing Multiple Anti-Hepatitis C Virus shRNAs and Their Validation on a Novel HCV Replicon Double Reporter Cell Line

Despite the introduction of directly acting antivirals (DAAs), for the treatment of hepatitis C virus (HCV) infection, their cost, patient compliance, and viral resistance are still important issues to be considered. Here, we describe the generation of a novel JFH1-based HCV subgenomic replicon doub...

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Detalles Bibliográficos
Autores principales: Elbadawy, Hossein M., Mohammed Abdul, Mohi I., Aljuhani, Naif, Vitiello, Adriana, Ciccarese, Francesco, Shaker, Mohamed A., Eltahir, Heba M., Palù, Giorgio, Di Antonio, Veronica, Ghassabian, Hanieh, Del Vecchio, Claudia, Salata, Cristiano, Franchin, Elisa, Ponterio, Eleonora, Bahashwan, Saleh, Thabet, Khaled, Abouzied, Mekky M., Shehata, Ahmed M., Parolin, Cristina, Calistri, Arianna, Alvisi, Gualtiero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551853/
https://www.ncbi.nlm.nih.gov/pubmed/32962117
http://dx.doi.org/10.3390/v12091044

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