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Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs

Fumonisin contamination in corn is an emerging issue in animal feed production. Fumonisin disrupts the metabolism of sphingolipids and reduces growth performance. This experiment was conducted to determine the effect of feeding fumonisin-contaminated corn on growth performance and sphinganine (SA) t...

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Autores principales: Rao, Zhong-Xing, Tokach, Mike D., Woodworth, Jason C., DeRouchey, Joel M., Goodband, Robert D., Calderón, Hilda I., Dritz, Steve S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551907/
https://www.ncbi.nlm.nih.gov/pubmed/32961935
http://dx.doi.org/10.3390/toxins12090604
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author Rao, Zhong-Xing
Tokach, Mike D.
Woodworth, Jason C.
DeRouchey, Joel M.
Goodband, Robert D.
Calderón, Hilda I.
Dritz, Steve S.
author_facet Rao, Zhong-Xing
Tokach, Mike D.
Woodworth, Jason C.
DeRouchey, Joel M.
Goodband, Robert D.
Calderón, Hilda I.
Dritz, Steve S.
author_sort Rao, Zhong-Xing
collection PubMed
description Fumonisin contamination in corn is an emerging issue in animal feed production. Fumonisin disrupts the metabolism of sphingolipids and reduces growth performance. This experiment was conducted to determine the effect of feeding fumonisin-contaminated corn on growth performance and sphinganine (SA) to sphingosine (SO) ratios of 9 to 28 kg pigs. A total of 350 pigs, were used with 5 pigs/pen and 14 pens/treatment. Dietary treatments contained fumonisin-contaminated corn (50 mg/kg of fumonisin B1 + B2) blended with low fumonisin corn (10 mg/kg of fumonisin B1 + B2) to provide dietary fumonisin concentrations of 7.2, 14.7, 21.9, 32.7, and 35.1 mg/kg. From day 0 to 28, increasing fumonisin concentration decreased (linear, p < 0.001) average daily gain, average daily feed intake (linear, p = 0.055), and gain:feed ratio (linear, p = 0.016). Although these response criteria tested linear, the greatest reduction in performance was in pigs fed with 32.7 and 35.1 mg/kg of fumonisin (B1 + B2). Increasing fumonisin concentration increased the serum SA:SO ratio (linear, p < 0.001) on day 14 and 28. In summary, for 9 to 28 kg nursery pigs, increasing fumonisin linearly decreased average daily gain and gain:feed ratio. However, despite the linear response, diets containing up to 21.9 mg/kg of fumonisin did not have as dramatic a decrease in growth performance as those fed more than 32.7 mg/kg. Further research is warranted to determine the effect of fumonisin concentrations between 21.9 and 32.7 mg/kg.
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spelling pubmed-75519072020-10-14 Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs Rao, Zhong-Xing Tokach, Mike D. Woodworth, Jason C. DeRouchey, Joel M. Goodband, Robert D. Calderón, Hilda I. Dritz, Steve S. Toxins (Basel) Article Fumonisin contamination in corn is an emerging issue in animal feed production. Fumonisin disrupts the metabolism of sphingolipids and reduces growth performance. This experiment was conducted to determine the effect of feeding fumonisin-contaminated corn on growth performance and sphinganine (SA) to sphingosine (SO) ratios of 9 to 28 kg pigs. A total of 350 pigs, were used with 5 pigs/pen and 14 pens/treatment. Dietary treatments contained fumonisin-contaminated corn (50 mg/kg of fumonisin B1 + B2) blended with low fumonisin corn (10 mg/kg of fumonisin B1 + B2) to provide dietary fumonisin concentrations of 7.2, 14.7, 21.9, 32.7, and 35.1 mg/kg. From day 0 to 28, increasing fumonisin concentration decreased (linear, p < 0.001) average daily gain, average daily feed intake (linear, p = 0.055), and gain:feed ratio (linear, p = 0.016). Although these response criteria tested linear, the greatest reduction in performance was in pigs fed with 32.7 and 35.1 mg/kg of fumonisin (B1 + B2). Increasing fumonisin concentration increased the serum SA:SO ratio (linear, p < 0.001) on day 14 and 28. In summary, for 9 to 28 kg nursery pigs, increasing fumonisin linearly decreased average daily gain and gain:feed ratio. However, despite the linear response, diets containing up to 21.9 mg/kg of fumonisin did not have as dramatic a decrease in growth performance as those fed more than 32.7 mg/kg. Further research is warranted to determine the effect of fumonisin concentrations between 21.9 and 32.7 mg/kg. MDPI 2020-09-18 /pmc/articles/PMC7551907/ /pubmed/32961935 http://dx.doi.org/10.3390/toxins12090604 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rao, Zhong-Xing
Tokach, Mike D.
Woodworth, Jason C.
DeRouchey, Joel M.
Goodband, Robert D.
Calderón, Hilda I.
Dritz, Steve S.
Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs
title Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs
title_full Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs
title_fullStr Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs
title_full_unstemmed Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs
title_short Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs
title_sort effects of fumonisin-contaminated corn on growth performance of 9 to 28 kg nursery pigs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551907/
https://www.ncbi.nlm.nih.gov/pubmed/32961935
http://dx.doi.org/10.3390/toxins12090604
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