Reducing False Negative PCR Test for COVID-19

As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not t...

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Autores principales: Bahreini, Fatemeh, Najafi, Rezvan, Amini, Razieh, Khazaei, Salman, Bashirian, Saeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Global Health and Education Projects, Inc 2020
Materias:
Letter to the Editor | Covid-19 Test
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552113/
https://www.ncbi.nlm.nih.gov/pubmed/33072432
http://dx.doi.org/10.21106/ijma.421
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author Bahreini, Fatemeh
Najafi, Rezvan
Amini, Razieh
Khazaei, Salman
Bashirian, Saeid
author_facet Bahreini, Fatemeh
Najafi, Rezvan
Amini, Razieh
Khazaei, Salman
Bashirian, Saeid
author_sort Bahreini, Fatemeh
collection PubMed
description As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not taken into consideration when performing this test, it can have a relatively large number of false negative results. In this article, we discuss important considerations that could lead to false negative test reduction.
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spelling pubmed-75521132020-10-16 Reducing False Negative PCR Test for COVID-19 Bahreini, Fatemeh Najafi, Rezvan Amini, Razieh Khazaei, Salman Bashirian, Saeid Int J MCH AIDS Letter to the Editor | Covid-19 Test As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not taken into consideration when performing this test, it can have a relatively large number of false negative results. In this article, we discuss important considerations that could lead to false negative test reduction. Global Health and Education Projects, Inc 2020 2020-10-08 /pmc/articles/PMC7552113/ /pubmed/33072432 http://dx.doi.org/10.21106/ijma.421 Text en Copyright © 2020 Bahreini et al. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor | Covid-19 Test
Bahreini, Fatemeh
Najafi, Rezvan
Amini, Razieh
Khazaei, Salman
Bashirian, Saeid
Reducing False Negative PCR Test for COVID-19
title Reducing False Negative PCR Test for COVID-19
title_full Reducing False Negative PCR Test for COVID-19
title_fullStr Reducing False Negative PCR Test for COVID-19
title_full_unstemmed Reducing False Negative PCR Test for COVID-19
title_short Reducing False Negative PCR Test for COVID-19
title_sort reducing false negative pcr test for covid-19
topic Letter to the Editor | Covid-19 Test
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552113/
https://www.ncbi.nlm.nih.gov/pubmed/33072432
http://dx.doi.org/10.21106/ijma.421
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