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Survey on Sheep Usage in Biomedical Research

SIMPLE SUMMARY: Sheep are used in biomedical research. A European survey was conducted with the goal of identifying the need for improvement in the use of sheep. Most participants were veterinarians working at academic institutions. Two thirds have been working with sheep for more than 5 years, and...

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Autores principales: Berset, Corina Mihaela, Lanker, Urban, Zeiter, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552153/
https://www.ncbi.nlm.nih.gov/pubmed/32872575
http://dx.doi.org/10.3390/ani10091528
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author Berset, Corina Mihaela
Lanker, Urban
Zeiter, Stephan
author_facet Berset, Corina Mihaela
Lanker, Urban
Zeiter, Stephan
author_sort Berset, Corina Mihaela
collection PubMed
description SIMPLE SUMMARY: Sheep are used in biomedical research. A European survey was conducted with the goal of identifying the need for improvement in the use of sheep. Most participants were veterinarians working at academic institutions. Two thirds have been working with sheep for more than 5 years, and their answers emphasized the importance of healthy sheep to be used in biomedical research, as about 60% have encountered health problems not related to study protocol. Other important points were sheep availability and the trust into and experience of the sheep supplier. This survey identified important points for refinement in the use of sheep in biomedical research with health status and monitoring as possible starting points. ABSTRACT: Currently, there is a lack of detailed information about sheep used for biomedical research. Therefore, a European survey was conducted among sheep users gathering information on the current situation, with emphasis on animal selection criteria and issues encountered in practice. The ultimate goal was to identify needs for improvement, which will subsequently lead to a refinement and reduction of the total number of animals used for experimental studies. From the 84 respondents, 77.4% were veterinarians, 71.4% were employed at academic institutions and 63.1% had worked with sheep as research animals for more than 5 years. The majority of the respondents were using females (79.8%) with no clear age preference, mainly for surgical procedures and testing medical devices. The main criteria for choosing a sheep supplier were the animals’ health status, their availability, the trust and experience in the sheep provider and the animals’ uniformity. Approximately 60% of the respondents had encountered problems in their sheep not related to the experimental protocol and almost half of them did not have a health monitoring program for their animals. In conclusion, there is definitely a need for refinement in selecting sheep used in biomedical research, with their health status as possible starting point.
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spelling pubmed-75521532020-10-16 Survey on Sheep Usage in Biomedical Research Berset, Corina Mihaela Lanker, Urban Zeiter, Stephan Animals (Basel) Communication SIMPLE SUMMARY: Sheep are used in biomedical research. A European survey was conducted with the goal of identifying the need for improvement in the use of sheep. Most participants were veterinarians working at academic institutions. Two thirds have been working with sheep for more than 5 years, and their answers emphasized the importance of healthy sheep to be used in biomedical research, as about 60% have encountered health problems not related to study protocol. Other important points were sheep availability and the trust into and experience of the sheep supplier. This survey identified important points for refinement in the use of sheep in biomedical research with health status and monitoring as possible starting points. ABSTRACT: Currently, there is a lack of detailed information about sheep used for biomedical research. Therefore, a European survey was conducted among sheep users gathering information on the current situation, with emphasis on animal selection criteria and issues encountered in practice. The ultimate goal was to identify needs for improvement, which will subsequently lead to a refinement and reduction of the total number of animals used for experimental studies. From the 84 respondents, 77.4% were veterinarians, 71.4% were employed at academic institutions and 63.1% had worked with sheep as research animals for more than 5 years. The majority of the respondents were using females (79.8%) with no clear age preference, mainly for surgical procedures and testing medical devices. The main criteria for choosing a sheep supplier were the animals’ health status, their availability, the trust and experience in the sheep provider and the animals’ uniformity. Approximately 60% of the respondents had encountered problems in their sheep not related to the experimental protocol and almost half of them did not have a health monitoring program for their animals. In conclusion, there is definitely a need for refinement in selecting sheep used in biomedical research, with their health status as possible starting point. MDPI 2020-08-30 /pmc/articles/PMC7552153/ /pubmed/32872575 http://dx.doi.org/10.3390/ani10091528 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Berset, Corina Mihaela
Lanker, Urban
Zeiter, Stephan
Survey on Sheep Usage in Biomedical Research
title Survey on Sheep Usage in Biomedical Research
title_full Survey on Sheep Usage in Biomedical Research
title_fullStr Survey on Sheep Usage in Biomedical Research
title_full_unstemmed Survey on Sheep Usage in Biomedical Research
title_short Survey on Sheep Usage in Biomedical Research
title_sort survey on sheep usage in biomedical research
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552153/
https://www.ncbi.nlm.nih.gov/pubmed/32872575
http://dx.doi.org/10.3390/ani10091528
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