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The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy

Genetic mutations and abnormal gene regulation are key mechanisms underlying tumorigenesis. Nucleosomes, which consist of DNA wrapped around histone cores, represent the basic units of chromatin. The fifth amino group (N(ε)) of histone lysine residues is a common site for post-translational modifica...

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Detalles Bibliográficos
Autores principales:	Li, Guo, Tian, Yuan, Zhu, Wei-Guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552186/ https://www.ncbi.nlm.nih.gov/pubmed/33117804 http://dx.doi.org/10.3389/fcell.2020.576946

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