Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1

Zinc finger E-box binding homeobox 1 (Zeb1) has been demonstrated to participate in the acquisition of the properties of cancer stem cells (CSCs). However, it is largely unknown how signals from the tumor microenvironment (TME) contribute to aberrant Zeb1 expression. Here, we show that Zeb1 depletio...

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Detalles Bibliográficos
Autores principales: Jiang, Huimin, Zhou, Chen, Zhang, Zhen, Wang, Qiong, Wei, Huimin, Shi, Wen, Li, Jianjun, Wang, Zhaoyang, Ou, Yang, Wang, Wenhao, Wang, Hang, Zhang, Quansheng, Sun, Wei, Sun, Peiqing, Yang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552407/
https://www.ncbi.nlm.nih.gov/pubmed/33046710
http://dx.doi.org/10.1038/s41467-020-18860-4

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