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MethHaplo: combining allele-specific DNA methylation and SNPs for haplotype region identification

BACKGROUND: DNA methylation is an important epigenetic modification that plays a critical role in most eukaryotic organisms. Parental alleles in haploid genomes may exhibit different methylation patterns, which can lead to different phenotypes and even different therapeutic and drug responses to dis...

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Detalles Bibliográficos
Autores principales: Zhou, Qiangwei, Wang, Ze, Li, Jing, Sung, Wing-Kin, Li, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552496/
https://www.ncbi.nlm.nih.gov/pubmed/33045983
http://dx.doi.org/10.1186/s12859-020-03798-7