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MethHaplo: combining allele-specific DNA methylation and SNPs for haplotype region identification
BACKGROUND: DNA methylation is an important epigenetic modification that plays a critical role in most eukaryotic organisms. Parental alleles in haploid genomes may exhibit different methylation patterns, which can lead to different phenotypes and even different therapeutic and drug responses to dis...
Autores principales: | Zhou, Qiangwei, Wang, Ze, Li, Jing, Sung, Wing-Kin, Li, Guoliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552496/ https://www.ncbi.nlm.nih.gov/pubmed/33045983 http://dx.doi.org/10.1186/s12859-020-03798-7 |
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