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Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial)
OBJECTIVES: To assess the efficacy of several repurposed drugs to prevent hospitalisation or death in patients aged 65 or more with recent symptomatic SARS-CoV-2 infection (COVID-19) and no criteria for hospitalisation. TRIAL DESIGN: Phase III, multi-arm (5) and multi-stage (MAMS), randomized, open-...
Autores principales: | Duvignaud, Alexandre, Lhomme, Edouard, Pistone, Thierry, Onaisi, Racha, Sitta, Rémi, Journot, Valérie, Nguyen, Duc, Peiffer-Smadja, Nathan, Crémer, Antoine, Bouchet, Stéphane, Darnaud, Thomas, Poitrenaud, Delphine, Piroth, Lionel, Binquet, Christine, Michel, Jean-François, Lefèvre, Benjamin, Lebeaux, David, Lebel, Josselin, Dupouy, Julie, Roussillon, Caroline, Gimbert, Anne, Wittkop, Linda, Thiébaut, Rodolphe, Orne-Gliemann, Joanna, Joseph, Jean-Philippe, Richert, Laura, Anglaret, Xavier, Malvy, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552584/ https://www.ncbi.nlm.nih.gov/pubmed/33050924 http://dx.doi.org/10.1186/s13063-020-04619-1 |
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