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Bioreactor Parameters for Microcarrier-Based Human MSC Expansion under Xeno-Free Conditions in a Vertical-Wheel System

Human mesenchymal stem/stromal cells (hMSCs) have been investigated and proven to be a well-tolerated, safe therapy for a variety of indications, as shown by over 900 registered hMSC-based clinical trials. To meet the commercial demand for clinical manufacturing of hMSCs, production requires a scale...

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Detalles Bibliográficos
Autores principales:	Lembong, Josephine, Kirian, Robert, Takacs, Joseph D., Olsen, Timothy R., Lock, Lye Theng, Rowley, Jon A., Ahsan, Tabassum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552727/ https://www.ncbi.nlm.nih.gov/pubmed/32650422 http://dx.doi.org/10.3390/bioengineering7030073

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