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The Helminth Parasite Heligmosomoides polygyrus Attenuates EAE in an IL-4Rα-Dependent Manner

Helminth parasites are effective in biasing Th2 immunity and inducing regulatory pathways that minimize excessive inflammation within their hosts, thus allowing chronic infection to occur whilst also suppressing bystander atopic or autoimmune diseases. Multiple sclerosis (MS) is a severe autoimmune...

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Detalles Bibliográficos
Autores principales: White, Madeleine P. J., Johnston, Chris J. C., Grainger, John R., Konkel, Joanne E., O'Connor, Richard A., Anderton, Stephen M., Maizels, Rick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552805/
https://www.ncbi.nlm.nih.gov/pubmed/33117327
http://dx.doi.org/10.3389/fimmu.2020.01830