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Hemorrhagic Bullous Lichen Sclerosus: A Case Report

Patient: Female, 63-year-old Final Diagnosis: Lichen sclerosus Symptoms: Itching skin Medication: — Clinical Procedure: Biopsy Specialty: Dermatology OBJECTIVE: Rare disease BACKGROUND: Lichen sclerosus (LS) is a chronic autoimmune dermatosis characterized by white, sclerotic, atrophic plaques. Clas...

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Autores principales: Khatib, Jude, Wargo, Jeffrey J., Krishnamurthy, Smita, Travers, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552941/
https://www.ncbi.nlm.nih.gov/pubmed/33024070
http://dx.doi.org/10.12659/AJCR.919353
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author Khatib, Jude
Wargo, Jeffrey J.
Krishnamurthy, Smita
Travers, Jeffrey B.
author_facet Khatib, Jude
Wargo, Jeffrey J.
Krishnamurthy, Smita
Travers, Jeffrey B.
author_sort Khatib, Jude
collection PubMed
description Patient: Female, 63-year-old Final Diagnosis: Lichen sclerosus Symptoms: Itching skin Medication: — Clinical Procedure: Biopsy Specialty: Dermatology OBJECTIVE: Rare disease BACKGROUND: Lichen sclerosus (LS) is a chronic autoimmune dermatosis characterized by white, sclerotic, atrophic plaques. Classic LS commonly occurs in the anogenital region, while extragenital lichen sclerosis typically occurs on the trunk and proximal extremities. Bullous lichen sclerosus is a rare variant that can occur in both genital and extragenital LS. Flaccid bullae can form, which may become hemorrhagic and produce a characteristic appearance clinically. CASE REPORT: In this report, we describe the case of a 63-year-old female patient who presented for evaluation of a rapidly growing, erythematous, scaly growth on her back/shoulder that was biopsied and found to be hemorrhagic bullous LS. We will discuss the clinical and histologic features of this case as well as treatment of bullous LS, which in this case was a topical high-potency corticosteroid. CONCLUSIONS: Bullous LS has been poorly studied due to the rarity of the condition, with limited investigation of the clinical and histopathologic characteristics of bullous LS and the available treatment options. Although rare, extragenital LS with hemorrhagic bullous features is an important variant of LS that should be considered to ensure appropriate diagnosis and treatment.
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spelling pubmed-75529412020-10-31 Hemorrhagic Bullous Lichen Sclerosus: A Case Report Khatib, Jude Wargo, Jeffrey J. Krishnamurthy, Smita Travers, Jeffrey B. Am J Case Rep Articles Patient: Female, 63-year-old Final Diagnosis: Lichen sclerosus Symptoms: Itching skin Medication: — Clinical Procedure: Biopsy Specialty: Dermatology OBJECTIVE: Rare disease BACKGROUND: Lichen sclerosus (LS) is a chronic autoimmune dermatosis characterized by white, sclerotic, atrophic plaques. Classic LS commonly occurs in the anogenital region, while extragenital lichen sclerosis typically occurs on the trunk and proximal extremities. Bullous lichen sclerosus is a rare variant that can occur in both genital and extragenital LS. Flaccid bullae can form, which may become hemorrhagic and produce a characteristic appearance clinically. CASE REPORT: In this report, we describe the case of a 63-year-old female patient who presented for evaluation of a rapidly growing, erythematous, scaly growth on her back/shoulder that was biopsied and found to be hemorrhagic bullous LS. We will discuss the clinical and histologic features of this case as well as treatment of bullous LS, which in this case was a topical high-potency corticosteroid. CONCLUSIONS: Bullous LS has been poorly studied due to the rarity of the condition, with limited investigation of the clinical and histopathologic characteristics of bullous LS and the available treatment options. Although rare, extragenital LS with hemorrhagic bullous features is an important variant of LS that should be considered to ensure appropriate diagnosis and treatment. International Scientific Literature, Inc. 2020-10-07 /pmc/articles/PMC7552941/ /pubmed/33024070 http://dx.doi.org/10.12659/AJCR.919353 Text en © Am J Case Rep, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Khatib, Jude
Wargo, Jeffrey J.
Krishnamurthy, Smita
Travers, Jeffrey B.
Hemorrhagic Bullous Lichen Sclerosus: A Case Report
title Hemorrhagic Bullous Lichen Sclerosus: A Case Report
title_full Hemorrhagic Bullous Lichen Sclerosus: A Case Report
title_fullStr Hemorrhagic Bullous Lichen Sclerosus: A Case Report
title_full_unstemmed Hemorrhagic Bullous Lichen Sclerosus: A Case Report
title_short Hemorrhagic Bullous Lichen Sclerosus: A Case Report
title_sort hemorrhagic bullous lichen sclerosus: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552941/
https://www.ncbi.nlm.nih.gov/pubmed/33024070
http://dx.doi.org/10.12659/AJCR.919353
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