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Dynamics models for identifying the key transmission parameters of the COVID-19 disease

After the analysis and forecast of COVID-19 spreading in China, Italy, and France the WHO has declared the COVID-19 a pandemic. There are around 100 research groups across the world trying to develop a vaccine for this coronavirus. Therefore, the quantitative and qualitative analysis of the COVID–19...

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Autores principales: Shahzad, Muhammad, Abdel-Aty, Abdel-Haleem, Attia, Raghda A.M., Khoshnaw, Sarbaz H.A., Aldila, Dipo, Ali, Mehboob, Sultan, Faisal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552992/
http://dx.doi.org/10.1016/j.aej.2020.10.006
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author Shahzad, Muhammad
Abdel-Aty, Abdel-Haleem
Attia, Raghda A.M.
Khoshnaw, Sarbaz H.A.
Aldila, Dipo
Ali, Mehboob
Sultan, Faisal
author_facet Shahzad, Muhammad
Abdel-Aty, Abdel-Haleem
Attia, Raghda A.M.
Khoshnaw, Sarbaz H.A.
Aldila, Dipo
Ali, Mehboob
Sultan, Faisal
author_sort Shahzad, Muhammad
collection PubMed
description After the analysis and forecast of COVID-19 spreading in China, Italy, and France the WHO has declared the COVID-19 a pandemic. There are around 100 research groups across the world trying to develop a vaccine for this coronavirus. Therefore, the quantitative and qualitative analysis of the COVID–19 pandemic is needed along with the effect of rapid test infection identification on controlling the spread of COVID-19. Mathematical models with computational simulations are the effective tools that help global efforts to estimate key transmission parameters and further improvements for controlling this disease. This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. In this paper, we develop the models for coronavirus disease at different stages with the addition of more parameters due to interactions among the individuals. Then, some key computational simulations and sensitivity analysis are investigated. Further, the local sensitivities for each model state concerning the model parameters are computed using the model reduction techniques: the dynamical models are eventually changed with the change of parameters are represented graphically.
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spelling pubmed-75529922020-10-13 Dynamics models for identifying the key transmission parameters of the COVID-19 disease Shahzad, Muhammad Abdel-Aty, Abdel-Haleem Attia, Raghda A.M. Khoshnaw, Sarbaz H.A. Aldila, Dipo Ali, Mehboob Sultan, Faisal Alexandria Engineering Journal Article After the analysis and forecast of COVID-19 spreading in China, Italy, and France the WHO has declared the COVID-19 a pandemic. There are around 100 research groups across the world trying to develop a vaccine for this coronavirus. Therefore, the quantitative and qualitative analysis of the COVID–19 pandemic is needed along with the effect of rapid test infection identification on controlling the spread of COVID-19. Mathematical models with computational simulations are the effective tools that help global efforts to estimate key transmission parameters and further improvements for controlling this disease. This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. In this paper, we develop the models for coronavirus disease at different stages with the addition of more parameters due to interactions among the individuals. Then, some key computational simulations and sensitivity analysis are investigated. Further, the local sensitivities for each model state concerning the model parameters are computed using the model reduction techniques: the dynamical models are eventually changed with the change of parameters are represented graphically. The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. 2021-02 2020-10-13 /pmc/articles/PMC7552992/ http://dx.doi.org/10.1016/j.aej.2020.10.006 Text en © 2020 The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Shahzad, Muhammad
Abdel-Aty, Abdel-Haleem
Attia, Raghda A.M.
Khoshnaw, Sarbaz H.A.
Aldila, Dipo
Ali, Mehboob
Sultan, Faisal
Dynamics models for identifying the key transmission parameters of the COVID-19 disease
title Dynamics models for identifying the key transmission parameters of the COVID-19 disease
title_full Dynamics models for identifying the key transmission parameters of the COVID-19 disease
title_fullStr Dynamics models for identifying the key transmission parameters of the COVID-19 disease
title_full_unstemmed Dynamics models for identifying the key transmission parameters of the COVID-19 disease
title_short Dynamics models for identifying the key transmission parameters of the COVID-19 disease
title_sort dynamics models for identifying the key transmission parameters of the covid-19 disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552992/
http://dx.doi.org/10.1016/j.aej.2020.10.006
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