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Modulation of CXCR4-Mediated Gi1 Activation by EGF Receptor and GRK2
[Image: see text] The CXCL12 chemokine receptor CXCR4 belongs to the GPCR superfamily and is often overexpressed in cancer, being involved in tumor progression and metastasis. How CXCR4 signaling integrates with other relevant oncogenic transduction pathways and the role of GPCR regulatory mechanism...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553016/ https://www.ncbi.nlm.nih.gov/pubmed/33073183 http://dx.doi.org/10.1021/acsptsci.0c00021 |