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Modulation of CXCR4-Mediated Gi1 Activation by EGF Receptor and GRK2

[Image: see text] The CXCL12 chemokine receptor CXCR4 belongs to the GPCR superfamily and is often overexpressed in cancer, being involved in tumor progression and metastasis. How CXCR4 signaling integrates with other relevant oncogenic transduction pathways and the role of GPCR regulatory mechanism...

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Detalles Bibliográficos
Autores principales:	Neves, Maria, Perpiñá-Viciano, Cristina, Penela, Petronila, Hoffmann, Carsten, Mayor, Federico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553016/ https://www.ncbi.nlm.nih.gov/pubmed/33073183 http://dx.doi.org/10.1021/acsptsci.0c00021

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