Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders

[Image: see text] COVID-19 is a global pandemic, thus requiring multiple strategies to develop modalities against it. Herein, we designed multiple bioactive small molecules that target a functional structure within the SARS-CoV-2’s RNA genome, the causative agent of COVID-19. An analysis to characte...

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Detalles Bibliográficos
Autores principales: Haniff, Hafeez S., Tong, Yuquan, Liu, Xiaohui, Chen, Jonathan L., Suresh, Blessy M., Andrews, Ryan J., Peterson, Jake M., O’Leary, Collin A., Benhamou, Raphael I., Moss, Walter N., Disney, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553039/
https://www.ncbi.nlm.nih.gov/pubmed/33140033
http://dx.doi.org/10.1021/acscentsci.0c00984

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