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Incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (COVID-19) pandemic()

AIMS: The hospitalization of patients with MI has decreased during global lockdown due to the COVID-19 pandemic. Whether this decrease is associated with more severe MI, e.g. MI-CS, is unknown. We aimed to examine the association of Corona virus disease (COVID-19) pandemic and incidence of acute myo...

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Autores principales: Lauridsen, M.D., Butt, J.H., Østergaard, L., Møller, J.E., Hassager, C., Gerds, T., Kragholm, K., Phelps, M., Schou, M., Torp-Pedersen, C., Gislason, G., Køber, L., Fosbøl, E.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553065/
https://www.ncbi.nlm.nih.gov/pubmed/33072848
http://dx.doi.org/10.1016/j.ijcha.2020.100659
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author Lauridsen, M.D.
Butt, J.H.
Østergaard, L.
Møller, J.E.
Hassager, C.
Gerds, T.
Kragholm, K.
Phelps, M.
Schou, M.
Torp-Pedersen, C.
Gislason, G.
Køber, L.
Fosbøl, E.L.
author_facet Lauridsen, M.D.
Butt, J.H.
Østergaard, L.
Møller, J.E.
Hassager, C.
Gerds, T.
Kragholm, K.
Phelps, M.
Schou, M.
Torp-Pedersen, C.
Gislason, G.
Køber, L.
Fosbøl, E.L.
author_sort Lauridsen, M.D.
collection PubMed
description AIMS: The hospitalization of patients with MI has decreased during global lockdown due to the COVID-19 pandemic. Whether this decrease is associated with more severe MI, e.g. MI-CS, is unknown. We aimed to examine the association of Corona virus disease (COVID-19) pandemic and incidence of acute myocardial infarction with cardiogenic shock (MI-CS). METHODS: On March 11, 2020, the Danish government announced national lock-down. Using Danish nationwide registries, we identified patients hospitalized with MI-CS. Incidence rates (IR) and incidence rate ratios (IRR) were used to compare MI-CS before and after March 11 in 2015–2019 and in 2020. RESULTS: We identified 11,769 patients with MI of whom 696 (5.9%) had cardiogenic shock in 2015–2019. In 2020, 2132 MI patients were identified of whom 119 had cardiogenic shock (5.6%). The IR per 100,000 person years before March 11 in 2015–2019 was 9.2 (95% CI: 8.3–10.2) and after 8.9 (95% CI: 8.0–9.9). In 2020, the IR was 7.5 (95% CI: 5.8–9.7) before March 11 and 7.7 (95% CI: 6.0–9.9) after. The IRRs comparing the 2020-period with the 2015–2019 period before and after March 11 (lockdown) were 0.81 (95% CI: 0.59–1.12) and 0.87 (95% CI: 0.57–1.32), respectively. The IRR comparing the 2020-period during and before lockdown was 1.02 (95% CI: 0.74–1.41). No difference in 7-day mortality or in-hospital management was observed between study periods. CONCLUSION: We could not identify a significant association of the national lockdown on the incidence of MI-CS, along with similar in-hospital management and mortality in patients with MI-CS.
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spelling pubmed-75530652020-10-13 Incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (COVID-19) pandemic() Lauridsen, M.D. Butt, J.H. Østergaard, L. Møller, J.E. Hassager, C. Gerds, T. Kragholm, K. Phelps, M. Schou, M. Torp-Pedersen, C. Gislason, G. Køber, L. Fosbøl, E.L. Int J Cardiol Heart Vasc Original Paper AIMS: The hospitalization of patients with MI has decreased during global lockdown due to the COVID-19 pandemic. Whether this decrease is associated with more severe MI, e.g. MI-CS, is unknown. We aimed to examine the association of Corona virus disease (COVID-19) pandemic and incidence of acute myocardial infarction with cardiogenic shock (MI-CS). METHODS: On March 11, 2020, the Danish government announced national lock-down. Using Danish nationwide registries, we identified patients hospitalized with MI-CS. Incidence rates (IR) and incidence rate ratios (IRR) were used to compare MI-CS before and after March 11 in 2015–2019 and in 2020. RESULTS: We identified 11,769 patients with MI of whom 696 (5.9%) had cardiogenic shock in 2015–2019. In 2020, 2132 MI patients were identified of whom 119 had cardiogenic shock (5.6%). The IR per 100,000 person years before March 11 in 2015–2019 was 9.2 (95% CI: 8.3–10.2) and after 8.9 (95% CI: 8.0–9.9). In 2020, the IR was 7.5 (95% CI: 5.8–9.7) before March 11 and 7.7 (95% CI: 6.0–9.9) after. The IRRs comparing the 2020-period with the 2015–2019 period before and after March 11 (lockdown) were 0.81 (95% CI: 0.59–1.12) and 0.87 (95% CI: 0.57–1.32), respectively. The IRR comparing the 2020-period during and before lockdown was 1.02 (95% CI: 0.74–1.41). No difference in 7-day mortality or in-hospital management was observed between study periods. CONCLUSION: We could not identify a significant association of the national lockdown on the incidence of MI-CS, along with similar in-hospital management and mortality in patients with MI-CS. Elsevier 2020-10-13 /pmc/articles/PMC7553065/ /pubmed/33072848 http://dx.doi.org/10.1016/j.ijcha.2020.100659 Text en © 2020 The Authors. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Paper
Lauridsen, M.D.
Butt, J.H.
Østergaard, L.
Møller, J.E.
Hassager, C.
Gerds, T.
Kragholm, K.
Phelps, M.
Schou, M.
Torp-Pedersen, C.
Gislason, G.
Køber, L.
Fosbøl, E.L.
Incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (COVID-19) pandemic()
title Incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (COVID-19) pandemic()
title_full Incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (COVID-19) pandemic()
title_fullStr Incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (COVID-19) pandemic()
title_full_unstemmed Incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (COVID-19) pandemic()
title_short Incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (COVID-19) pandemic()
title_sort incidence of acute myocardial infarction-related cardiogenic shock during corona virus disease 19 (covid-19) pandemic()
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553065/
https://www.ncbi.nlm.nih.gov/pubmed/33072848
http://dx.doi.org/10.1016/j.ijcha.2020.100659
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