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Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2
Host proteases have been suggested to be crucial for dissemination of MERS, SARS-CoV, and SARS-CoV-2 coronaviruses, but the relative contribution of membrane versus intracellular proteases remains controversial. Transmembrane serine protease 2 (TMPRSS2) is regarded as one of the main proteases impli...
Autores principales: | Azouz, Nurit P., Klingler, Andrea M., Callahan, Victoria, Akhrymuk, Ivan V., Elez, Katarina, Raich, Lluís, Henry, Brandon M., Benoit, Justin L., Benoit, Stefanie W., Noé, Frank, Kehn-Hall, Kylene, Rothenberg, Marc E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553163/ https://www.ncbi.nlm.nih.gov/pubmed/33052338 http://dx.doi.org/10.1101/2020.05.04.077826 |
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