Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2

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Host proteases have been suggested to be crucial for dissemination of MERS, SARS-CoV, and SARS-CoV-2 coronaviruses, but the relative contribution of membrane versus intracellular proteases remains controversial. Transmembrane serine protease 2 (TMPRSS2) is regarded as one of the main proteases impli...

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Detalles Bibliográficos
Autores principales: Azouz, Nurit P., Klingler, Andrea M., Callahan, Victoria, Akhrymuk, Ivan V., Elez, Katarina, Raich, Lluís, Henry, Brandon M., Benoit, Justin L., Benoit, Stefanie W., Noé, Frank, Kehn-Hall, Kylene, Rothenberg, Marc E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553163/
https://www.ncbi.nlm.nih.gov/pubmed/33052338
http://dx.doi.org/10.1101/2020.05.04.077826
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