CUP-AI-Dx: A tool for inferring cancer tissue of origin and molecular subtype using RNA gene-expression data and artificial intelligence

BACKGROUND: Cancer of unknown primary (CUP), representing approximately 3-5% of all malignancies, is defined as metastatic cancer where a primary site of origin cannot be found despite a standard diagnostic workup. Because knowledge of a patient's primary cancer remains fundamental to their tre...

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Detalles Bibliográficos
Autores principales: Zhao, Yue, Pan, Ziwei, Namburi, Sandeep, Pattison, Andrew, Posner, Atara, Balachander, Shiva, Paisie, Carolyn A., Reddi, Honey V, Rueter, Jens, Gill, Anthony J, Fox, Stephen, Raghav, Kanwal P.S., Flynn, William F, Tothill, Richard W., Li, Sheng, Karuturi, R. Krishna Murthy, George, Joshy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553237/
https://www.ncbi.nlm.nih.gov/pubmed/33039710
http://dx.doi.org/10.1016/j.ebiom.2020.103030

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