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Pharmacokinetics and Biodistribution of Thymoquinone-loaded Nanostructured Lipid Carrier After Oral and Intravenous Administration into Rats
BACKGROUND: Thymoquinone (TQ), an active compound isolated from Nigella sativa, has been proven to exhibit various biological properties such as antioxidant. Although oral delivery of TQ is valuable, it is limited by poor oral bioavailability and low solubility. Recently, TQ-loaded nanostructured li...
Autores principales: | Zakarial Ansar, Fatin Hannani, Latifah, Saiful Yazan, Wan Kamal, Wan Hamirul Bahrin, Khong, Khei Choong, Ng, Yen, Foong, Jia Ning, Gopalsamy, Banulata, Ng, Wei Keat, How, Chee Wun, Ong, Yong Sze, Abdullah, Rasedee, Aziz, Mohd Yusmaidie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553255/ https://www.ncbi.nlm.nih.gov/pubmed/33116496 http://dx.doi.org/10.2147/IJN.S262395 |
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