Cargando…

RNF128 Promotes Malignant Behaviors via EGFR/MEK/ERK Pathway in Hepatocellular Carcinoma

BACKGROUND: The ubiquitin-proteasome system participates in the pathogenesis and progression of hepatocellular carcinoma (HCC). As an E3 ubiquitin ligase, RNF128 has been proved vital in carcinogenesis, whereas, little is known about the oncogenic mechanisms of RNF128 in HCC. MATERIALS AND METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bai, Xue-Song, Zhang, Chi, Peng, Rui, Jiang, Guo-Qing, Jin, Sheng-Jie, Wang, Qian, Ke, Ai-Wu, Bai, Dou-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553654/ https://www.ncbi.nlm.nih.gov/pubmed/33116595 http://dx.doi.org/10.2147/OTT.S269606

Ejemplares similares

RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma
por: Zhou, Jie, et al.
Publicado: (2023)

RNF128 Promotes Invasion and Metastasis Via the EGFR/MAPK/MMP-2 Pathway in Esophageal Squamous Cell Carcinoma
por: Gao, Jing, et al.
Publicado: (2019)

Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma
por: Peng, Rui, et al.
Publicado: (2019)

RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury
por: Liu, Pei-Yao, et al.
Publicado: (2023)

Bee venom-loaded EGFR-targeting peptide-coupled chitosan nanoparticles for effective therapy of hepatocellular carcinoma by inhibiting EGFR-mediated MEK/ERK pathway
por: Abdulmalek, Shaymaa, et al.
Publicado: (2022)

Retraction: Bee venom-loaded EGFR-targeting peptide-coupled chitosan nanoparticles for effective therapy of hepatocellular carcinoma by inhibiting EGFR-mediated MEK/ERK pathway
Publicado: (2023)

In Vitro and In Vivo Efficacies of the EGFR/MEK/ERK Signaling Inhibitors in the Treatment of Alveolar Echinococcosis
por: Cheng, Zhe, et al.
Publicado: (2020)

Knockdown of RNF6 inhibits HeLa cervical cancer cell growth via suppression of MAPK/ERK signaling
por: Zhu, Kang, et al.
Publicado: (2021)

The MEK inhibitors enhance the efficacy of sorafenib against hepatocellular carcinoma cells through reducing p-ERK rebound
por: Hou, Wanting, et al.
Publicado: (2019)

Midazolam impedes lung carcinoma cell proliferation and migration via EGFR/MEK/ERK signaling pathway
por: Zhang, Xiangchao, et al.
Publicado: (2023)

SERPINA11 Inhibits Metastasis in Hepatocellular Carcinoma by Suppressing MEK/ERK Signaling Pathway
por: Song, Ye, et al.
Publicado: (2021)

RNF25 promotes gefitinib resistance in EGFR-mutant NSCLC cells by inducing NF-κB-mediated ERK reactivation
por: Cho, Jung Hee, et al.
Publicado: (2018)

Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses
por: Cao, Jun, et al.
Publicado: (2021)

Re-enforcing the strategy of targeting MEK/ERK signaling to overcome acquired resistance to third generation EGFR inhibitors
por: Zhao, Wen, et al.
Publicado: (2021)

Downregulation of RNF128 Predicts Progression and Poor Prognosis in Patients with Urothelial Carcinoma of the Upper Tract and Urinary Bladder
por: Lee, Yi-Ying, et al.
Publicado: (2016)

RNF128 expression in lung adenocarcinoma is a favorable prognostic factor associated with decreased tumor‐associated macrophages
por: Fujimoto, Syuusuke, et al.
Publicado: (2023)

Nanocomplexes loaded with miR-128-3p for enhancing chemotherapy effect of colorectal cancer through dual-targeting silence the activity of PI3K/AKT and MEK/ERK pathway
por: Liu, Xin, et al.
Publicado: (2020)

Does marital status impact postoperative survival in patients with less differentiated hepatocellular carcinoma? A population‐based study
por: Yan, Bing, et al.
Publicado: (2019)

Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway
por: Tseng, Ya-Shih, et al.
Publicado: (2009)

The prognostic correlation of AFP level at diagnosis with pathological grade, progression, and survival of patients with hepatocellular carcinoma
por: Bai, Dou-Sheng, et al.
Publicado: (2017)

The MEK/ERK/miR-21 Signaling Is Critical in Osimertinib Resistance in EGFR-Mutant Non-Small Cell Lung Cancer Cells
por: Huang, Wen-Chien, et al.
Publicado: (2021)

RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31
por: Chen, Xijun, et al.
Publicado: (2022)

MEK/ERK addiction in CNL/aCML
por: Kesarwani, Meenu, et al.
Publicado: (2017)

TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function
por: Principe, D R, et al.
Publicado: (2017)

The Extract of Rhodobacter sphaeroides Inhibits Melanogenesis through the MEK/ERK Signaling Pathway
por: Liu, Wen-Sheng, et al.
Publicado: (2013)

FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway
por: Li, Kun, et al.
Publicado: (2016)

Managing Acquired Resistance to Third-Generation EGFR Tyrosine Kinase Inhibitors Through Co-Targeting MEK/ERK Signaling
por: Yu, Danlei, et al.
Publicado: (2021)

Acute pancreatitis and obstructive jaundice as initial complaints of hepatocellular carcinoma: case report
por: Jiang, Guo-Qing, et al.
Publicado: (2014)

Differences in tumour characteristics of Hepatocellular Carcinoma between patients with and without Cirrhosis: A population-based study
por: Yan, Bing, et al.
Publicado: (2020)

RNF135 Promoter Methylation Is Associated With Immune Infiltration and Prognosis in Hepatocellular Carcinoma
por: Wang, Xiao, et al.
Publicado: (2022)

AS-703026 Inhibits LPS-Induced TNFα Production through MEK/ERK Dependent and Independent Mechanisms
por: Li, Ping, et al.
Publicado: (2015)

CDCA8 induced by NF-YA promotes hepatocellular carcinoma progression by regulating the MEK/ERK pathway
por: Chen, Erbao, et al.
Publicado: (2023)

Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation
por: Schweyer, S, et al.
Publicado: (2004)

A practical nomogram and risk stratification system predicting the cancer‐specific survival for patients with early hepatocellular carcinoma
por: Yan, Bing, et al.
Publicado: (2020)

Hexokinase 2 Promotes Cell Growth and Tumor Formation Through the Raf/MEK/ERK Signaling Pathway in Cervical Cancer
por: Cui, Nan, et al.
Publicado: (2020)

Growth Inhibitory Signaling of the Raf/MEK/ERK Pathway
por: Wu, Pui-Kei, et al.
Publicado: (2020)

The MEK/ERK Module Is Reprogrammed in Remodeling Adult Cardiomyocytes
por: Thomas, Kubin, et al.
Publicado: (2020)

The MEK5/ERK5 Pathway in Health and Disease
por: Paudel, Rupesh, et al.
Publicado: (2021)

Downregulation of RNF128 activates Wnt/β-catenin signaling to induce cellular EMT and stemness via CD44 and CTTN ubiquitination in melanoma
por: Wei, Chuan-Yuan, et al.
Publicado: (2019)

HSCs-derived COMP drives hepatocellular carcinoma progression by activating MEK/ERK and PI3K/AKT signaling pathways
por: Li, Qing, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dcn2g2ohh77bt1i5l4pfjm59ce