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Small-molecule inhibitors of TBK1 serve as an adjuvant for a plasmid-launched live-attenuated yellow fever vaccine
Plasmid-launched live-attenuated vaccines (PLLAV), also called infectious DNA (iDNA) vaccines, combine the assets of genetic immunization with the potency of replication-competent live viral vaccines. However, due to their origin as bacterial plasmid DNA, efficient delivery of PLLAV may be hampered...
Autores principales: | Sharma, Sapna, Schmid, Michael A., Sanchez Felipe, Lorena, Grenelle, Jana, Kaptein, Suzanne J.F., Coelmont, Lotte, Neyts, Johan, Dallmeier, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553677/ https://www.ncbi.nlm.nih.gov/pubmed/32574095 http://dx.doi.org/10.1080/21645515.2020.1765621 |
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