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Small-molecule inhibitors of TBK1 serve as an adjuvant for a plasmid-launched live-attenuated yellow fever vaccine

Plasmid-launched live-attenuated vaccines (PLLAV), also called infectious DNA (iDNA) vaccines, combine the assets of genetic immunization with the potency of replication-competent live viral vaccines. However, due to their origin as bacterial plasmid DNA, efficient delivery of PLLAV may be hampered...

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Detalles Bibliográficos
Autores principales: Sharma, Sapna, Schmid, Michael A., Sanchez Felipe, Lorena, Grenelle, Jana, Kaptein, Suzanne J.F., Coelmont, Lotte, Neyts, Johan, Dallmeier, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553677/
https://www.ncbi.nlm.nih.gov/pubmed/32574095
http://dx.doi.org/10.1080/21645515.2020.1765621

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