Integrating genotypes and phenotypes improves long-term forecasts of seasonal influenza A/H3N2 evolution

Seasonal influenza virus A/H3N2 is a major cause of death globally. Vaccination remains the most effective preventative. Rapid mutation of hemagglutinin allows viruses to escape adaptive immunity. This antigenic drift necessitates regular vaccine updates. Effective vaccine strains need to represent...

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Detalles Bibliográficos
Autores principales: Huddleston, John, Barnes, John R, Rowe, Thomas, Xu, Xiyan, Kondor, Rebecca, Wentworth, David E, Whittaker, Lynne, Ermetal, Burcu, Daniels, Rodney Stuart, McCauley, John W, Fujisaki, Seiichiro, Nakamura, Kazuya, Kishida, Noriko, Watanabe, Shinji, Hasegawa, Hideki, Barr, Ian, Subbarao, Kanta, Barrat-Charlaix, Pierre, Neher, Richard A, Bedford, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553778/
https://www.ncbi.nlm.nih.gov/pubmed/32876050
http://dx.doi.org/10.7554/eLife.60067

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