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Thiamine Deficiency With Mashed Potatoes: A Novel Case of Wernicke Encephalopathy Manifesting With Retinal Hemorrhages in a Pediatric Patient
We present a case report of a 17-year-old obese female with one-week onset of progressive confusion and double vision, associated with 50-pound weight loss in five months. On fundus examination, retinal hemorrhages and abnormalities of eye movements were seen. MRI showed abnormalities that were cons...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553792/ https://www.ncbi.nlm.nih.gov/pubmed/33062542 http://dx.doi.org/10.7759/cureus.10429 |
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author | Tiwana, Harmanpreet K Raymond, Gerald Littleton, Kevin Singhal, Rishi Kumar, Ashutosh |
author_facet | Tiwana, Harmanpreet K Raymond, Gerald Littleton, Kevin Singhal, Rishi Kumar, Ashutosh |
author_sort | Tiwana, Harmanpreet K |
collection | PubMed |
description | We present a case report of a 17-year-old obese female with one-week onset of progressive confusion and double vision, associated with 50-pound weight loss in five months. On fundus examination, retinal hemorrhages and abnormalities of eye movements were seen. MRI showed abnormalities that were consistent with diagnosis of Wernicke encephalopathy (WE). Thiamine replacement caused gradual improvement in patient’s symptoms. Peripapillary hemorrhages on fundus examination, as seen in our patient, have been rarely seen in WE. Obesity with retinal hemorrhages, diplopia, etc. can be misleading due to idiopathic intracranial hypertension being the most common presentation in this subset. Thus, fundoscopy should be part of routine examination in WE-suspected patients. |
format | Online Article Text |
id | pubmed-7553792 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-75537922020-10-14 Thiamine Deficiency With Mashed Potatoes: A Novel Case of Wernicke Encephalopathy Manifesting With Retinal Hemorrhages in a Pediatric Patient Tiwana, Harmanpreet K Raymond, Gerald Littleton, Kevin Singhal, Rishi Kumar, Ashutosh Cureus Neurology We present a case report of a 17-year-old obese female with one-week onset of progressive confusion and double vision, associated with 50-pound weight loss in five months. On fundus examination, retinal hemorrhages and abnormalities of eye movements were seen. MRI showed abnormalities that were consistent with diagnosis of Wernicke encephalopathy (WE). Thiamine replacement caused gradual improvement in patient’s symptoms. Peripapillary hemorrhages on fundus examination, as seen in our patient, have been rarely seen in WE. Obesity with retinal hemorrhages, diplopia, etc. can be misleading due to idiopathic intracranial hypertension being the most common presentation in this subset. Thus, fundoscopy should be part of routine examination in WE-suspected patients. Cureus 2020-09-13 /pmc/articles/PMC7553792/ /pubmed/33062542 http://dx.doi.org/10.7759/cureus.10429 Text en Copyright © 2020, Tiwana et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Neurology Tiwana, Harmanpreet K Raymond, Gerald Littleton, Kevin Singhal, Rishi Kumar, Ashutosh Thiamine Deficiency With Mashed Potatoes: A Novel Case of Wernicke Encephalopathy Manifesting With Retinal Hemorrhages in a Pediatric Patient |
title | Thiamine Deficiency With Mashed Potatoes: A Novel Case of Wernicke Encephalopathy Manifesting With Retinal Hemorrhages in a Pediatric Patient |
title_full | Thiamine Deficiency With Mashed Potatoes: A Novel Case of Wernicke Encephalopathy Manifesting With Retinal Hemorrhages in a Pediatric Patient |
title_fullStr | Thiamine Deficiency With Mashed Potatoes: A Novel Case of Wernicke Encephalopathy Manifesting With Retinal Hemorrhages in a Pediatric Patient |
title_full_unstemmed | Thiamine Deficiency With Mashed Potatoes: A Novel Case of Wernicke Encephalopathy Manifesting With Retinal Hemorrhages in a Pediatric Patient |
title_short | Thiamine Deficiency With Mashed Potatoes: A Novel Case of Wernicke Encephalopathy Manifesting With Retinal Hemorrhages in a Pediatric Patient |
title_sort | thiamine deficiency with mashed potatoes: a novel case of wernicke encephalopathy manifesting with retinal hemorrhages in a pediatric patient |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553792/ https://www.ncbi.nlm.nih.gov/pubmed/33062542 http://dx.doi.org/10.7759/cureus.10429 |
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