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Leptin alters energy intake and fat mass but not energy expenditure in lean subjects

Based on studies in mice, leptin was expected to decrease body weight in obese individuals. However, the majority of the obese are hyperleptinemic and do not respond to leptin treatment, suggesting the presence of leptin tolerance and questioning the role of leptin as regulator of energy balance in...

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Detalles Bibliográficos
Autores principales:	Chrysafi, Pavlina, Perakakis, Nikolaos, Farr, Olivia M., Stefanakis, Konstantinos, Peradze, Natia, Sala-Vila, Aleix, Mantzoros, Christos S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553922/ https://www.ncbi.nlm.nih.gov/pubmed/33051459 http://dx.doi.org/10.1038/s41467-020-18885-9

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