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Integrated clinico-molecular profiling of appendiceal adenocarcinoma reveals a unique grade-driven entity distinct from colorectal cancer
BACKGROUND: Appendiceal adenocarcinoma (AA) is an orphan disease with unique clinical attributes but often treated as colorectal cancer (CRC). Understanding key molecular differences between AA and CRC is critical. METHODS: We performed retrospective analyses of AA patients (N = 266) with tumour and...
Autores principales: | Raghav, Kanwal, Shen, John P., Jácome, Alexandre A., Guerra, Jennifer L., Scally, Christopher P., Taggart, Melissa W., Foo, Wai C., Matamoros, Aurelio, Shaw, Kenna R., Fournier, Keith, Overman, Michael J., Eng, Cathy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553941/ https://www.ncbi.nlm.nih.gov/pubmed/32733093 http://dx.doi.org/10.1038/s41416-020-1015-3 |
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