Poly (ADP-ribose) polymerase inhibitor exposure reduces ovarian reserve followed by dysfunction in granulosa cells

The use of poly (ADP-ribose) polymerase (PARP) inhibitors is expected to increase, but their effect on fertility is still unclear. The aim of this study was to investigate the effect of PARP inhibitors on ovarian function. In an in vitro study, cultures of ovaries and granulosa cells (GCs) exposed t...

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Detalles Bibliográficos
Autores principales: Nakamura, Kentaro, Takae, Seido, Shiraishi, Eriko, Shinya, Kiemi, Igualada, Arby Jane, Suzuki, Nao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553950/
https://www.ncbi.nlm.nih.gov/pubmed/33051529
http://dx.doi.org/10.1038/s41598-020-74087-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553950/
https://www.ncbi.nlm.nih.gov/pubmed/33051529
http://dx.doi.org/10.1038/s41598-020-74087-9

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