Wnt/β-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells

OBJECTIVE: Canonical Wnt/β-catenin signaling is a well-studied endogenous regulator of mesenchymal cell fate determination, promoting osteoblastogenesis and inhibiting adipogenesis. However, emerging genetic evidence in humans links a number of Wnt pathway members to body fat distribution, obesity,...

Descripción completa

Detalles Bibliográficos
Autores principales: Bagchi, Devika P., Nishii, Akira, Li, Ziru, DelProposto, Jennifer B., Corsa, Callie A., Mori, Hiroyuki, Hardij, Julie, Learman, Brian S., Lumeng, Carey N., MacDougald, Ormond A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554252/
https://www.ncbi.nlm.nih.gov/pubmed/32919095
http://dx.doi.org/10.1016/j.molmet.2020.101078

Ejemplares similares

Ejemplares similares