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Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress, predicts all-cause and cardiovascular mortality in the general population

BACKGROUND: Inherited methylmalonic acidemia is characterized by mitochondrial dysfunction, oxidative stress, and damage of mitochondria-rich organs in children. It is unclear whether methylmalonic acid (MMA) is related to poor prognosis in adults. The study aims to investigate the associations of M...

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Detalles Bibliográficos
Autores principales:	Wang, Shanjie, Liu, Yige, Liu, Jinxin, Tian, Wei, Zhang, Xiaoyuan, Cai, Hengxuan, Fang, Shaohong, Yu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554255/ https://www.ncbi.nlm.nih.gov/pubmed/33035815 http://dx.doi.org/10.1016/j.redox.2020.101741

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