A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imagi...

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Detalles Bibliográficos
Autores principales: Uraguchi, Kensuke, Kozakura, Kenichi, Oka, Satoshi, Higaki, Takaya, Makihara, Seiichiro, Imai, Toshi, Doi, Akira, Ohta, Tsuyoshi, Kariya, Shin, Nishizaki, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554319/
https://www.ncbi.nlm.nih.gov/pubmed/33083212
http://dx.doi.org/10.1016/j.mmcr.2020.09.004
Descripción
Sumario:A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.

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