lncRNA HotairM1 Depletion Promotes Self-Renewal of Cancer Stem Cells through HOXA1-Nanog Regulation Loop

In cancer cells, a gain of stemness may have profound implications for tumor initiation, aggressiveness, and clinical outcome. However, the molecular mechanisms underlying the self-renewal maintenance of cancer stem-like cells (CSCs) remain elusive. Here, based on analysis of transcriptome sequencin...

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Detalles Bibliográficos
Autores principales: Li, Fang, Xu, Yangfan, Xu, Xiaofang, Ge, Shengfang, Zhang, Feifei, Zhang, He, Fan, Xianqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554324/
https://www.ncbi.nlm.nih.gov/pubmed/33230449
http://dx.doi.org/10.1016/j.omtn.2020.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554324/
https://www.ncbi.nlm.nih.gov/pubmed/33230449
http://dx.doi.org/10.1016/j.omtn.2020.09.008

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