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Amelioration of Compound 48/80-Mediated Itch and LL-37-Induced Inflammation by a Single-Stranded Oligonucleotide

Numerous inflammatory skin disorders display a high prevalence of itch. The Mas-related G protein coupled receptor X2 (MRGPRX2) has been shown to modulate itch by inducing non-IgE-mediated mast cell degranulation and the release of endogenous inducers of pruritus. Various substances collectively kno...

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Detalles Bibliográficos
Autores principales: Dondalska, Aleksandra, Rönnberg, Elin, Ma, Haisha, Pålsson, Sandra Axberg, Magnusdottir, Elin, Gao, Tianle, Adam, Lucille, Lerner, Ethan A., Nilsson, Gunnar, Lagerström, Malin, Spetz, Anna-Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554336/
https://www.ncbi.nlm.nih.gov/pubmed/33101278
http://dx.doi.org/10.3389/fimmu.2020.559589