The Impact of Air Pollution on Hospitalization for Cardiovascular and Cerebrovascular Disease in Shenyang, China

BACKGROUND: The aim of this study was to investigate the overall impact of PM(2.5), PM(10), NO(2), SO(2), CO, and O(3) on the admission of cardiovascular and cerebrovascular disease. METHODS: We collected data on cardiovascular and cerebrovascular disease admissions from two hospitals in Shenyang Liaoning, China from Jan 2014 to Dec 2017, as well as daily measurements of six pollutants at 11 sites in Shenyang. The generalized additive model was used to assess the association between daily contaminants and admission to cardiovascular and cerebrovascular disease. RESULTS: The single-contamination model showed a significant correlation between NO(2), O(3), PM(10) and cardiovascular and cerebrovascular diseases at lag0 day. Air pollutants had lag effects on different gender groups. Excess relative risks (ERs) associated with a 10 μg/m(3) increase were 1.522(1.057, 1.988) on lag02 for NO(2), 0.547% (0.367%, 0.728%), 0.133% (0.061%, 0.205%) on lag3 for O(3) and PM(10). The dual pollutant model showed that the effects of NO(2), O(3), and PM(10) after adjusting the influence of other pollutants were still statistically significant. CONCLUSION: Short-term exposure to ambient air pollution (NO(2), O(3), and PM(10)) may be associated with an increased risk of daily cardiovascular and cerebrovascular admission, which may provide reliable evidence for further understanding of the potential adverse effects of air pollution on cardiovascular and cerebrovascular diseases.