Cargando…

Perspectives on mechanistic implications of ROS inducers for targeting viral infections

In this perspective, we propose to leverage reactive oxygen species (ROS) induction as a potential therapeutic measure against viral infections. Our rationale for targeting RNA viral infections by pro-oxidants is routed on the mechanistic hypothesis that ROS based treatment paradigm could impair RNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nadhan, Revathy, Patra, Dipyaman, Krishnan, Neethu, Rajan, Arathi, Gopala, Srinivas, Ravi, Dashnamoorthy, Srinivas, Priya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2021
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554476/ https://www.ncbi.nlm.nih.gov/pubmed/33068588 http://dx.doi.org/10.1016/j.ejphar.2020.173621

Ejemplares similares

Cytological Grading of Breast Tumors—The Human and Canine Perspective
por: Kuppusamy, Krithiga, et al.
Publicado: (2019)

Brcal Defective Breast Cancer Cells Induce in vitro Transformation of Cancer Associated Fibroblasts (CAFs) to Metastasis Associated Fibroblasts (MAF)
por: Hemalatha, Sreelatha K., et al.
Publicado: (2018)

Preparation and Evaluation of Ribonuclease-Resistant Viral HIV RNA Standards Based on Armored RNA Technology
por: Gholami, Mohammad, et al.
Publicado: (2018)

Targeting pivotal inflammatory pathways in COVID-19: A mechanistic review
por: Yarmohammadi, Akram, et al.
Publicado: (2021)

Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures
por: Madsen, Jesper J., et al.
Publicado: (2022)

A ROS-responsive synergistic delivery system for combined immunotherapy and chemotherapy
por: Hu, Doudou, et al.
Publicado: (2022)

Glucose/ROS cascade-responsive ceria nanozymes for diabetic wound healing
por: Yu, Xiaojuan, et al.
Publicado: (2022)

Towards a thermodynamic mechanistic model for the effect of temperature on arthropod vector competence for transmission of arboviruses
por: Gale, Paul
Publicado: (2019)

ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment
por: Muhammad, Wali, et al.
Publicado: (2022)

ROS-responsive PEGylated ferrocene polymer nanoparticles with improved stability for tumor-selective chemotherapy and imaging
por: Oh, Hyeryeon, et al.
Publicado: (2023)

Allosteric inhibition of TEM‐1 β lactamase: Microsecond molecular dynamics simulations provide mechanistic insights
por: Hellemann, Erich, et al.
Publicado: (2023)

Association of HDAC8 Expression with Pathological Findings in Triple Negative and Non-Triple Negative Breast Cancer: Implications for Diagnosis
por: Menbari, Mohammad-Nazir, et al.
Publicado: (2020)

ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment
por: Tan, Chen, et al.
Publicado: (2022)

Oxidative metabolism is impaired by phosphate deficiency during fracture healing and is mechanistically related to BMP induced chondrocyte differentiation
por: Hussein, Amira I., et al.
Publicado: (2023)

ROS and Lipid Droplet accumulation induced by high glucose exposure in healthy colon and Colorectal Cancer Stem Cells
por: Tirinato, Luca, et al.
Publicado: (2019)

Drug-independent NADPH-consuming micelles collaborate with ROS-generator for cascade ferroptosis amplification by impairing redox homeostasis
por: Yu, Fangying, et al.
Publicado: (2023)

Inheritance of physico-chemical properties and ROS generation by carbon quantum dots derived from pyrolytically carbonized bacterial sources
por: Wu, Y., et al.
Publicado: (2021)

ROS-responsive nanoparticle-mediated delivery of CYP2J2 gene for therapeutic angiogenesis in severe hindlimb ischemia
por: Gui, Liang, et al.
Publicado: (2021)

Increased sensitivity of BRCA defective triple negative breast tumors to plumbagin through induction of DNA Double Strand Breaks (DSB)
por: Nair, Rakesh Sathish, et al.
Publicado: (2016)

Analogous amino acid sequences in myelin proteolipid and viral proteins
por: Shaw, Shyh-Yu, et al.
Publicado: (1986)

Multiplexed bio-imaging using cadmium telluride quantum dots synthesized by mathematically derived process parameters in a continuous flow active microreactor
por: Pandey, S., et al.
Publicado: (2021)

Functional and evolutionary analysis of viral proteins containing a Rossmann‐like fold
por: Medvedev, Kirill E., et al.
Publicado: (2018)

Proinflammatory cytokines are associated with prolonged viral RNA shedding in COVID-19 patients
por: Gao, Chun, et al.
Publicado: (2020)

Versatile nanorobot hand biosensor for specific capture and ultrasensitive quantification of viral nanoparticles
por: Li, Rui, et al.
Publicado: (2022)

A Genomic, Evolutionary, and Mechanistic Study of MCR‐5 Action Suggests Functional Unification across the MCR Family of Colistin Resistance
por: Zhang, Huimin, et al.
Publicado: (2019)

Tissue distributions of antiviral drugs affect their capabilities of reducing viral loads in COVID-19 treatment
por: Wang, Yan, et al.
Publicado: (2020)

Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage
por: Waltl, Inken, et al.
Publicado: (2018)

Host and viral proteins involved in SARS‐CoV‐2 infection differentially bind heme
por: Hopp, Marie‐T., et al.
Publicado: (2022)

Implication of COVID-19 outbreak on ship survey and certification
por: Nam, Dong, et al.
Publicado: (2021)

Fused in sarcoma undergoes cold denaturation: Implications for phase separation
por: Félix, Sara S., et al.
Publicado: (2023)

Qualitative perspectives toward prostitution's perceived lifestyle addictiveness
por: Firmin, Michael W., et al.
Publicado: (2013)

Effects of time perspective and self-control on procrastination and Internet addiction
por: Kim, Jinha, et al.
Publicado: (2017)

Macrophage responses associated with COVID-19: A pharmacological perspective
por: Booz, George W., et al.
Publicado: (2020)

Hospitalist perspectives on buprenorphine treatment for inpatients with opioid use disorder
por: Reed, Megan K, et al.
Publicado: (2022)

Berries anthocyanins as potential SARS-CoV–2 inhibitors targeting the viral attachment and replication; molecular docking simulation
por: Messaoudi, Omar, et al.
Publicado: (2021)

The association between viral load and concurrent human papillomavirus infection at the genital and anal sites of young women and the impact of vaccination
por: van Eer, Kahren, et al.
Publicado: (2021)

Non-viral gene therapy using RNA interference with PDGFR-α mediated epithelial-mesenchymal transformation for proliferative vitreoretinopathy
por: Wang, Jiahao, et al.
Publicado: (2023)

Social implications of children’s smartphone addiction: The role of support networks and social engagement
por: Ihm, Jennifer
Publicado: (2018)

Comparing lengths and inclusion of information in storytelling videos: Implications for Hepatitis B education
por: Silliman, Miriam, et al.
Publicado: (2022)

The immediate and long-term effects of time perspective on Internet gaming disorder
por: Lukavská, Kateřina
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_r0sgu0k7h7b2jsugdsdvmueb75